Sale G E, Storb R
Exp Hematol. 1983 Nov;11(10):961-6.
In light of recent studies showing successful transplantation of both bony and stromal elements by marrow transplantation, we report an unexpected phenomenon occurring in a canine radiation chimera. Nine hundred fifty-six days after a successful and uneventful DLA-matched marrow allograft, a dog suddenly died of respiratory failure. Autopsy revealed extensive ossification of the lungs with multiple sites of trilineage marrow engraftment. The entire complement of bony elements can apparently be allografted using marrow grafting techniques.
鉴于最近的研究表明通过骨髓移植成功移植了骨和基质成分，我们报告了一只犬辐射嵌合体中出现的意外现象。在成功且顺利的DLA匹配骨髓同种异体移植956天后，一只狗突然死于呼吸衰竭。尸检显示肺部广泛骨化，有多个三系骨髓植入部位。显然，使用骨髓移植技术可以同种异体移植全部骨成分。
