McFadden M R, Mehan D J
J Urol. 1978 Mar;119(3):372-4. doi: 10.1016/s0022-5347(17)57494-7.
Testicular biopsies were done on 101 patients who underwent ligation of the internal spermatic vein as primary treatment for infertility. Retrospective analysis included evaluation of tubular thickening, Leydig cell hyperplasia, premature sloughing, maturation arrest and decreased spermatogenesis. A comparison was made of biopsy profiles, sperm counts and pregnancies in an attempt to determine further the value of testicular biopsy in the subfertile man. The pregnancy rate was 40 per cent over-all, with 32 per cent of the patients with tubular thickening reporting pregnancies. There was only 1 pregnancy in patients with Leydig cell hyperplasia. The controversial finding of premature sloughing had no consistent relationship to results.
对101例因不育症而接受精索内静脉结扎术作为主要治疗手段的患者进行了睾丸活检。回顾性分析包括对曲细精管增厚、间质细胞增生、过早脱落、成熟停滞和生精减少情况的评估。对活检结果、精子计数和妊娠情况进行了比较，以进一步确定睾丸活检对不育男性的价值。总体妊娠率为40%，曲细精管增厚的患者中有32%报告有妊娠情况。间质细胞增生的患者中仅有1例妊娠。有争议的过早脱落这一发现与结果没有一致的关联。
