Vissink A, Waterman H A, s-Gravenmade E J, Panders A K, Vermey A
J Oral Pathol. 1984 Feb;13(1):22-8. doi: 10.1111/j.1600-0714.1984.tb01397.x.
Apparent viscosities at different shear rates were measured for 3 types of saliva substitutes: (a) mucin-containing saliva; (b) substitutes based upon carboxymethylcellulose (CMC), and (c) solution of polyethylenoxide (PEO). The apparent viscosities were compared with those of human whole saliva. Human whole saliva and mucin-containing saliva substitutes appeared to be similar in their rheological properties. Both types of solution are viscoelastic solutions and adjust their apparent viscosities to their biological functions. Preparations containing CMC or PEO are non-Newtonian liquids. From this study it is concluded that mucin-containing saliva substitutes appear to be the best substitutes for natural saliva, as far as rheological properties are concerned.
对3种类型的唾液替代品在不同剪切速率下的表观粘度进行了测量：(a)含粘蛋白的唾液；(b)基于羧甲基纤维素(CMC)的替代品；(c)聚环氧乙烷(PEO)溶液。将这些表观粘度与人类全唾液的表观粘度进行了比较。人类全唾液和含粘蛋白的唾液替代品在流变学性质上似乎相似。这两种溶液都是粘弹性溶液，并根据其生物学功能调整其表观粘度。含有CMC或PEO的制剂是非牛顿液体。从这项研究可以得出结论，就流变学性质而言，含粘蛋白的唾液替代品似乎是天然唾液的最佳替代品。
