Alhejoury Hajer Ayed, Mogharbel Lina Fouad, Al-Qadhi Mohammed Ahmed, Shamlan Suzan Sulaiman, Alturki Amal Fuad, Babatin Wafaa Mohammed, Mohammed Alaishan Renad Abdualrahman, Pullishery Fawaz
Dental Intern, Dentistry Program, Batterjee Medical College, Jeddah, Saudi Arabia.
General Dentist, Ministry of Health, King Abdulaziz University, Jeddah, Saudi Arabia.
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S903-S907. doi: 10.4103/jpbs.jpbs_236_21. Epub 2021 Nov 10.
In clinical practice, xerostomia or oral dryness is a chronic disease condition encountered by most dentists and dental hygienists, which often causes a negative impact on the oral health-related quality of life of the affected individual. Xerostomia is caused due to salivary gland dysfunction. It is related to reduced salivary secretion or the absence of saliva flow, more frequently, exhibits qualitative changes in saliva proteins and immunoglobulin concentrations that arise due to salivary gland dysfunction. This condition causes discomfort and interferes with normal oral activities, and affected individuals are at high caries risk. There are several options for treatment and symptom management: salivary stimulants, topical agents, saliva substitutes, and systemic sialogogues. This review explores the current status of therapeutic management of patients affected by xerostomia and hyposalivation using artificial saliva.
在临床实践中，口干症或口腔干燥是大多数牙医和口腔保健员会遇到的一种慢性病况，它常常会对受影响个体的口腔健康相关生活质量产生负面影响。口干症是由唾液腺功能障碍引起的。它与唾液分泌减少或唾液流缺失有关，更常见的是，由于唾液腺功能障碍，唾液蛋白质和免疫球蛋白浓度会出现质性变化。这种情况会引起不适并干扰正常的口腔活动，而且受影响个体患龋齿的风险很高。治疗和症状管理有几种选择：唾液刺激剂、局部用药、唾液替代品和全身性催涎剂。本综述探讨了使用人工唾液对受口干症和唾液分泌过少影响的患者进行治疗管理的现状。
