猴与人的前扣带回皮质与发声控制

The anterior cingulate cortex and the phonatory control in monkey and man.

作者信息

von Cramon D, Jürgens U

出版信息

Neurosci Biobehav Rev. 1983 Fall;7(3):423-5. doi: 10.1016/0149-7634(83)90049-0.

Abstract

Electrical stimulation of the anterior cingulate cortex yields vocalization in the monkey. The elicited vocalizations seem to represent primary stimulus responses. Monkeys are not able to perform a vocal conditioning task after ablation of the anterior cingulate cortex. However, they can carry out a lever-pressing conditioning task following destruction of this area. It is hypothesized that the anterior cingulate cortex exerts the volitional control of species-specific vocalizations in monkey. The non-verbal emotional vocal utterances are considered to be the human homologue of monkey's vocalizations. Therefore, bilateral lesion of the anterior cingulate cortex in man should hamper the volitional control of emotional vocal utterances in man as it does in monkeys. One personal observation is reported where after a bilateral infarction of the anterior cingulate cortex the patient's voice showed a permanent lack of emotional expression. The anterior cingulate cortex seems to play the decisive role in the volitional verbalization of emotions.

摘要

对猴子前扣带回皮层进行电刺激会引发其发声。所引发的发声似乎代表着初级刺激反应。在前扣带回皮层切除后，猴子无法完成发声条件反射任务。然而，在该区域被破坏后，它们能够执行杠杆按压条件反射任务。据推测，前扣带回皮层对猴子特定物种发声发挥着意志控制作用。非言语性情感发声被认为是猴子发声在人类中的同源物。因此，人类双侧前扣带回皮层损伤应会像在猴子中那样妨碍对人类情感发声的意志控制。报告了一项个人观察结果，一名患者在前扣带回皮层发生双侧梗塞后，其声音表现出永久性的情感表达缺失。前扣带回皮层似乎在情感的意志性言语表达中起决定性作用。