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人脑癫痫样棘波潜在空间分布源的神经磁学证据。

Neuromagnetic evidence of spatially distributed sources underlying epileptiform spikes in the human brain.

作者信息

Barth D S, Sutherling W, Engle J, Beatty J

出版信息

Science. 1984 Jan 20;223(4633):293-6. doi: 10.1126/science.6422552.

DOI:10.1126/science.6422552
PMID:6422552
Abstract

Neuromagnetic measurements were performed on 17 subjects with focal seizure disorders. In all of the subjects, the interictal spike in the scalp electroencephalogram was associated with an orderly extracranial magnetic field pattern. In eight of these subjects, multiple current sources underlay the magnetic spike complex. The multiple sources within a given subject displayed a fixed chronological sequence of discharge, demonstrating a high degree of spatial and temporal organization within the interictal focus.

摘要

对17名患有局灶性癫痫障碍的受试者进行了神经磁测量。在所有受试者中,头皮脑电图的发作间期棘波与有序的颅外磁场模式相关。在其中8名受试者中,磁棘波复合体有多个电流源。给定受试者体内的多个源显示出固定的放电时间顺序,表明发作间期病灶内具有高度的空间和时间组织性。

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