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[生物胺及其氧化脱氨基产物对兔肝γ-淀粉酶的抑制作用]

[Inhibition of gamma-amylase of the rabbit liver by biogenic amines and products of their oxidative deamination].

作者信息

Popova I A, Verevkina I V

出版信息

Vopr Med Khim. 1983 Nov-Dec;29(6):120-3.

PMID:6422628
Abstract

Products of oxidative deamination of biogenic amines (aldehydes) exhibited an inhibitory effect on rabbit liver gamma-amylase activity. The aldehydes, formed after serotonin and 2-phenylethylamine oxidation, proved to be most effective in these systems. Dopamine, noradrenaline and tyramine also caused a slight inhibitory action under these conditions. Biogenic amines and corresponding aldehydes participate apparently in regulation of gamma-amylolysis of glycogen in human and animal organisms.

摘要

生物胺(醛类)氧化脱氨产物对兔肝γ-淀粉酶活性具有抑制作用。血清素和2-苯乙胺氧化后形成的醛类在这些体系中被证明是最有效的。多巴胺、去甲肾上腺素和酪胺在这些条件下也会引起轻微的抑制作用。生物胺和相应的醛类显然参与了人和动物机体中糖原γ-淀粉酶解的调节。

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