Lowe A D, Lennox E S, Voak D
Vox Sang. 1984;46(1):29-35. doi: 10.1111/j.1423-0410.1984.tb00044.x.
By proper selection for good growth and high avidity, we have prepared a new anti-A monoclonal antibody producing cell line that gives culture supernatants as potent as US-licensed commercial hyperimmune human reagents and which meet USA FDA standards without the need for concentration. The production and use of this reagent is cost effective and makes it a candidate to replace conventional anti-A typing reagents.
通过适当选择以实现良好生长和高亲和力,我们制备了一种新的抗A单克隆抗体产生细胞系,该细胞系产生的培养上清液与美国许可的商业超免疫人试剂一样有效,并且无需浓缩即可符合美国食品药品监督管理局(FDA)标准。这种试剂的生产和使用具有成本效益,使其成为替代传统抗A分型试剂的候选者。