Aleksandrov A D, Antsiferova N G, Zhmyrina T I, Moroz A F
Zh Mikrobiol Epidemiol Immunobiol. 1984 Jan(1):14-9.
The possibility of using antigenic complexes contained in the extracellular slime of P. aeruginosa clinical strains belonging to different serological groups as the components of a chemical vaccine has been revealed. Animal experiments have demonstrated a high immunogenicity of these preparations, as well as their low toxicity. The use of slime antigens stimulates the production of specific antibodies exerting a protective action against infection with homologous P. aeruginosa strains.
已发现,将属于不同血清学组的铜绿假单胞菌临床菌株细胞外黏液中所含的抗原复合物用作化学疫苗的成分具有可能性。动物实验证明了这些制剂具有高免疫原性以及低毒性。使用黏液抗原可刺激产生特异性抗体,这些抗体对同源铜绿假单胞菌菌株感染具有保护作用。