Sullivan T Y, Yu P L
Am Rev Respir Dis. 1984 Jan;129(1):23-6. doi: 10.1164/arrd.1984.129.1.23.
It is unclear whether duration of the interval separating CO2 rebreathing tests has any effect on the CO2 response curve. In normal subjects, we compared slopes and intercepts, respectively, of CO2 response curves from 3 rebreathing tests separated by each of three different time intervals: 10, 20, and 30 min. The slopes and intercepts, respectively were no different from the first through third test with each interval and no different between tests from different intervals. Therefore, reproducibility of slope and intercept was not affected by the time interval separating each test. During each rebreathing test, heart rate and systolic blood pressure increased but diastolic blood pressure decreased. These effects resolved within 10 min after the test. We conclude that, in normal subjects, 3 CO2 rebreathing tests can be repeated rapidly with only 10 min of rest separating each test.
目前尚不清楚二氧化碳重复呼吸试验之间的间隔时间是否会对二氧化碳反应曲线产生任何影响。在正常受试者中，我们分别比较了三次重复呼吸试验的二氧化碳反应曲线的斜率和截距，这三次试验分别间隔三个不同的时间：10分钟、20分钟和30分钟。在每个间隔时间下，第一次到第三次试验的斜率和截距均无差异，不同间隔时间的试验之间也无差异。因此，每次试验之间的间隔时间不影响斜率和截距的可重复性。在每次重复呼吸试验期间，心率和收缩压升高，但舒张压降低。这些影响在试验后10分钟内消失。我们得出结论，在正常受试者中，三次二氧化碳重复呼吸试验可以快速重复进行，每次试验之间只需休息10分钟。
