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贝恩回路的重复呼吸特性。一项实验与理论研究。

Rebreathing characteristics of the Bain circuit. An experimental and theoretical study.

作者信息

Stenqvist O, Sonander H

出版信息

Br J Anaesth. 1984 Mar;56(3):303-10. doi: 10.1093/bja/56.3.303.

Abstract

The Bain circuit was studied in a model lung on the assumption that, in addition to the ratio of fresh gas flow to total ventilation (VFG/VE), different time fractions of the respiratory cycle might influence rebreathing. We found that the time fraction for active expiration (FEt) governed rebreathing for each VFG/VE value. With FEt as an independent variable, a theoretical formula was derived for rebreathing. Rearranging this formula made it possible to calculate the necessary increase in ventilation to keep end-tidal carbon dioxide constant for each VFG/VE. Thus, at a fresh gas flow of 70 ml kg-1 min-1, VI has to be increased 2.6 times. For spontaneously breathing patients inhalation anaesthetics that do not depress carbon dioxide sensitivity seem to be better suited to use in the Bain circuit. The FECO2 can then be kept constant through increased ventilation in spite of the concomitant increase in rebreathing.

摘要

在一个模拟肺模型中对贝恩回路进行了研究,假设除了新鲜气体流量与总通气量的比值(VFG/VE)外,呼吸周期的不同时间分数可能会影响重复呼吸。我们发现,主动呼气的时间分数(FEt)决定了每个VFG/VE值下的重复呼吸情况。以FEt作为自变量,推导出了一个关于重复呼吸的理论公式。对该公式进行重新整理后,就可以计算出为使每个VFG/VE值下的呼气末二氧化碳保持恒定所需增加的通气量。因此,在新鲜气体流量为70 ml·kg-1·min-1时,通气量(VI)必须增加2.6倍。对于自主呼吸的患者,似乎更适合在贝恩回路中使用不降低二氧化碳敏感性的吸入麻醉剂。尽管重复呼吸会随之增加,但通过增加通气量仍可使呼气末二氧化碳(FECO2)保持恒定。

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