Nguyen Douglas L, Limketkai Berkeley, Medici Valentina, Saire Mendoza Mardeli, Palmer Lena, Bechtold Matthew
Division of Gastroenterology & Hepatology, Department of Medicine, University of California-Irvine Medical Center, 101 The City Drive, Orange, CA, 92868, USA.
Department of Medicine, Stanford University, 300 Pasteur Dr, Palo Alto, CA, 94304, USA.
Curr Gastroenterol Rep. 2016 Oct;18(10):55. doi: 10.1007/s11894-016-0527-8.
Inflammatory bowel disease (IBD) is a group of chronic, lifelong, and relapsing illnesses, such as ulcerative colitis and Crohn's disease, which involve the gastrointestinal tract. There is no cure for these diseases, but combined pharmacological and nutritional therapy can induce remission and maintain clinical remission. Malnutrition and nutritional deficiencies among IBD patients result in poor clinical outcomes such as growth failure, reduced response to pharmacotherapy, increased risk for sepsis, and mortality. The aim of this review is to highlight the consequences of malnutrition in the management of IBD and describe nutritional interventions to facilitate induction of remission as well as maintenance; we will also discuss alternative delivery methods to improve nutritional status preoperatively.
炎症性肠病（IBD）是一组慢性、终身性且易复发的疾病，如溃疡性结肠炎和克罗恩病，累及胃肠道。这些疾病无法治愈，但药物治疗与营养治疗相结合可诱导缓解并维持临床缓解。IBD患者的营养不良和营养缺乏会导致不良临床结局，如生长发育迟缓、药物治疗反应降低、脓毒症风险增加及死亡率上升。本综述的目的是强调营养不良在IBD管理中的后果，并描述促进诱导缓解及维持缓解的营养干预措施；我们还将讨论改善术前营养状况的替代给药方法。
