维生素A治疗原发性胆汁性肝硬化的夜盲症。
Vitamin A treatment for night blindness in primary biliary cirrhosis.
作者信息
Walt R P, Kemp C M, Lyness L, Bird A C, Sherlock S
出版信息
Br Med J (Clin Res Ed). 1984 Apr 7;288(6423):1030-1. doi: 10.1136/bmj.288.6423.1030.
Abstract
Three patients with late stage primary biliary cirrhosis were found to have appreciable night blindness. Serum vitamin A concentrations were low in all three patients despite regular intramuscular supplementation in two. All patients responded dramatically to high dose oral supplementation, with full recovery of adaptation to dark and visual fields. Oral rather than intramuscular vitamin A supplementation seems appropriate in the prevention of ocular complications of vitamin A deficiency in biliary cirrhosis.
摘要
三名晚期原发性胆汁性肝硬化患者被发现有明显的夜盲症。尽管其中两名患者定期接受肌肉注射补充维生素A，但三名患者的血清维生素A浓度均较低。所有患者对高剂量口服补充剂均有显著反应，暗适应和视野完全恢复。在预防胆汁性肝硬化维生素A缺乏的眼部并发症方面，口服而非肌肉注射维生素A补充剂似乎更为合适。
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本文引用的文献
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