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[角黄素视网膜病变:1. 51名食用者的临床研究]

[Canthaxanthine retinopathy: 1. Clinical study in 51 consumers].

作者信息

Boudreault G, Cortin P, Corriveau L A, Rousseau A P, Tardif Y, Malenfant M

出版信息

Can J Ophthalmol. 1983 Dec;18(7):325-8.

PMID:6423246
Abstract

Canthaxanthine, a non-provitamin A carotenoid, has been marketed in Canada since March 1979 as a skin-tanning agent. Fifty-one individuals who ingested from 3.6 to 66 g of the drug within a 24-month period were ophthalmologically evaluated. Six of them had deposits in the ocular fundus that appeared to be related to ingestion of the substance, but no functional impairment could be detected.

摘要

角黄素,一种非维生素A类胡萝卜素,自1979年3月起在加拿大作为皮肤增色剂上市。对51名在24个月内摄入3.6至66克该药物的个体进行了眼科评估。其中6人眼底有沉积物,似乎与摄入该物质有关,但未检测到功能损害。

相似文献

1
[Canthaxanthine retinopathy: 1. Clinical study in 51 consumers].[角黄素视网膜病变:1. 51名食用者的临床研究]
Can J Ophthalmol. 1983 Dec;18(7):325-8.
2
[Retinopathy due to canthazanthine: 2. Predisposing factors].[角黄素所致视网膜病变:2. 诱发因素]
Can J Ophthalmol. 1984 Aug;19(5):215-9.
3
[Canthaxanthin retinopathy and macular pucker].[角黄素视网膜病变与黄斑皱襞]
J Fr Ophtalmol. 1989;12(12):891-6.
4
[Canthaxanthin retinopathy and macular pucker--clinical picture and ultrastructural findings of macular pucker].[角黄素视网膜病变与黄斑皱襞——黄斑皱襞的临床症状及超微结构研究结果]
Fortschr Ophthalmol. 1989;86(5):456-60.
5
Gold dust retinopathy after the ingestion of canthaxanthine to produce skin-bronzing.
Med J Aust. 1985;143(12-13):622-3. doi: 10.5694/j.1326-5377.1985.tb119974.x.
6
Crystalline retinopathy in patients taking an oral drug containing canthaxanthine.
Photodermatol. 1985 Jun;2(3):183-5.
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Canthaxanthine-induced retinal pigment epithelial changes in the cat.斑蝥黄质诱导猫视网膜色素上皮细胞变化
Curr Eye Res. 1988 Jul;7(7):687-93. doi: 10.3109/02713688809033198.
8
[Gold-dust maculopathy after absorption of canthaxanthine].
Bull Soc Ophtalmol Fr. 1983 Nov;83(11):1273-4, 1277.
9
Canthaxanthin retinopathy. Anatomic and functional reversibility.角黄素视网膜病变。解剖学和功能上的可逆性。
Arch Ophthalmol. 1989 Apr;107(4):538-40. doi: 10.1001/archopht.1989.01070010552029.
10
[Carotenoid retinopathy. I. Morphologic and functional findings].[类胡萝卜素视网膜病变。I. 形态学和功能学研究结果]
Klin Monbl Augenheilkd. 1985 May;186(5):351-4. doi: 10.1055/s-2008-1050936.

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Interactions between canthaxanthin and lipid membranes--possible mechanisms of canthaxanthin toxicity.角黄素与脂质膜之间的相互作用——角黄素毒性的可能机制。
Cell Mol Biol Lett. 2009;14(3):395-410. doi: 10.2478/s11658-009-0010-8. Epub 2009 Feb 12.
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The differential diagnosis of crystals in the retina.
Int Ophthalmol. 2001;24(3):113-21. doi: 10.1023/a:1021189215498.
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Experimental carotenoid retinopathy. I. Functional and morphological alterations of the rabbit retina after 11 months dietary carotenoid application.
Graefes Arch Clin Exp Ophthalmol. 1987;225(3):198-205. doi: 10.1007/BF02175449.
4
Canthaxanthin retinopathy. An investigation by light and electron microscopy and physicochemical analysis.角黄素视网膜病变。光镜、电镜及物理化学分析研究
Graefes Arch Clin Exp Ophthalmol. 1987;225(3):189-97. doi: 10.1007/BF02175448.