关于海蟾蜍离体视网膜中视杆细胞耦联的观察

Observations on rod coupling in the isolated retina of Bufo marinus.

作者信息

Griff E R, Pinto L H

出版信息

Vision Res. 1984;24(2):149-57. doi: 10.1016/0042-6989(84)90100-7.

Abstract

Rod coupling was studied in the superfused isolated retina of Bufo marinus. Pairs of interacting rods were simultaneously impaled; current injected into one rod caused a current-induced potential in the second rod. Current-induced potentials and input resistance were monitored while changing the superfusate. Interactions were not reduced by removing extracellular Na+ or Cl-, indicating that these conductances do not mediate coupling. Interactions were not eliminated by altering extracellular Ca2+ or decreasing intracellular pH; the interactions are thus resistant to treatments that uncouple cels in other systems.

摘要

在海蟾蜍的离体灌流视网膜中对杆体耦合进行了研究。同时刺入成对相互作用的杆体；向一根杆体注入电流会在第二根杆体中引起电流诱导电位。在改变灌流液的同时监测电流诱导电位和输入电阻。去除细胞外的Na⁺或Cl⁻并不会减少相互作用，这表明这些电导并不介导耦合。改变细胞外Ca²⁺或降低细胞内pH值并不会消除相互作用；因此，这些相互作用对其他系统中使细胞解耦联的处理具有抗性。