Mansbridge B, Fisher S
Psychopharmacology (Berl). 1984;82(3):225-8. doi: 10.1007/BF00427778.
A total of 147 outpatients waiting for a prescription to be filled at a hospital pharmacy were tested on their knowledge about diazepam (Valium). Subjects scored highest on questions about the effects of a small overdose, the drug's interaction with alcohol and hypnotics, and the relative contraindications of pregnancy and breast-feeding. Subjects were least knowledgeable about the drug's generic name, side effects, and interaction with minor stimulants (coffee, tea, cola, and cigarettes). Subjects who had previously used diazepam (N = 97) knew significantly more than subjects who had never taken it, but subjects waiting for a diazepam prescription to be filled (N = 40) were not more knowledgeable than subjects having another type of prescription filled. In contrast to recent findings that increasing patients' drug knowledge via "Patient Package Inserts" (PPIs) may also create an overcautious attitude toward the drug, the present study finds that diazepam knowledge gained experimentally is accompanied by an attitude shift away from such overcautiousness.
共有147名在医院药房等待取药的门诊患者接受了关于地西泮(安定)知识的测试。受试者在关于小剂量过量服用的影响、该药物与酒精及催眠药的相互作用以及妊娠和哺乳期相对禁忌方面的问题上得分最高。受试者对该药物的通用名、副作用以及与少量兴奋剂(咖啡、茶、可乐和香烟)的相互作用了解最少。以前使用过地西泮的受试者(N = 97)比从未服用过的受试者了解得多得多,但等待取地西泮处方的受试者(N = 40)并不比等待取其他类型处方的受试者知识更丰富。与近期的研究结果相反,即通过“患者用药指导”(PPI)增加患者的药物知识可能也会产生对药物过度谨慎的态度,本研究发现,通过实验获得的地西泮知识伴随着态度从这种过度谨慎中转变。