Chilosi M, Pizzolo G, Semenzato G, de Rossi G, Pandolfi F
Acta Haematol. 1984;71(4):277-81. doi: 10.1159/000206600.
The reactivity for the enzyme dipeptidyl-amino-peptidase IV (DAP IV) has been correlated, in 8 cases of T-cell chronic lymphocytic leukemia (T-CLL), with the cellular phenotype as well as the morphological and clinical behaviour of disease. A highly reproducible correspondence between the 'helper' phenotype (OKT4+/Fc mu-R+) and DAP IV expression was observed in cases with aggressive disease, whereas the cases with OKT8+/Fc mu-R+ phenotype was characterized by a favorable prognosis, LGL (large granular lymphocyte) morphology, and were virtually negative for DAP IV.
在8例T细胞慢性淋巴细胞白血病（T-CLL）中，已将二肽基氨基肽酶IV（DAP IV）的反应性与细胞表型以及疾病的形态学和临床行为相关联。在侵袭性疾病病例中观察到“辅助”表型（OKT4+/Fc mu-R+）与DAP IV表达之间具有高度可重复的对应关系，而具有OKT8+/Fc mu-R+表型的病例预后良好，具有大颗粒淋巴细胞（LGL）形态，并且DAP IV几乎呈阴性。
