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1
Resistance of Pseudomonas aeruginosa mutants with altered control of chromosomal beta-lactamase to piperacillin, ceftazidime, and cefsulodin.铜绿假单胞菌染色体β-内酰胺酶调控改变的突变体对哌拉西林、头孢他啶和头孢磺啶的耐药性。
Antimicrob Agents Chemother. 1984 Mar;25(3):382-4. doi: 10.1128/AAC.25.3.382.
2
Comparative in-vitro activity of cefsulodin and ceftazidime against ticarcillin-resistant Pseudomonas aeruginosa.头孢磺啶和头孢他啶对替卡西林耐药铜绿假单胞菌的体外比较活性
J Antimicrob Chemother. 1981 Sep;8 Suppl B:119-22. doi: 10.1093/jac/8.suppl_b.119.
3
Comparison of the beta-lactamase stability and the in-vitro activity of cefoperazone, cefotaxime, cefsulodin, ceftazidime, moxalactam and ceftriaxone against Pseudomonas aeruginosa.头孢哌酮、头孢噻肟、头孢磺啶、头孢他啶、拉氧头孢和头孢曲松对铜绿假单胞菌的β-内酰胺酶稳定性及体外活性比较。
J Antimicrob Chemother. 1981 Oct;8(4):323-31. doi: 10.1093/jac/8.4.323.
4
Susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.铜绿假单胞菌对β-内酰胺类抗生素的敏感性
Chemioterapia. 1985 Dec;4(6):424-8.
5
Resistant strains of Pseudomonas aeruginosa isolated after exposure to several beta-lactam antibiotics.在接触多种β-内酰胺类抗生素后分离出的铜绿假单胞菌耐药菌株。
Eur J Clin Microbiol. 1987 Feb;6(1):22-7. doi: 10.1007/BF02097185.
6
Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins.β-内酰胺酶AmpC突变增加铜绿假单胞菌分离株对抗假单胞菌头孢菌素的耐药性。
Antimicrob Agents Chemother. 2015 Oct;59(10):6248-55. doi: 10.1128/AAC.00825-15. Epub 2015 Jul 27.
7
Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa.解析铜绿假单胞菌头孢他啶-他唑巴坦耐药性的演变。
mBio. 2018 Dec 11;9(6):e02085-18. doi: 10.1128/mBio.02085-18.
8
Activity of Ceftolozane-Tazobactam and Ceftazidime-Avibactam against Beta-Lactam-Resistant Pseudomonas aeruginosa Isolates.头孢他洛滨-他唑巴坦和头孢他啶-阿维巴坦对β-内酰胺类耐药铜绿假单胞菌分离株的活性。
Antimicrob Agents Chemother. 2017 Nov 22;61(12). doi: 10.1128/AAC.01858-17. Print 2017 Dec.
9
Temperature-dependent expression of the chromosomal beta-lactamase gene in a strain of Pseudomonas aeruginosa.铜绿假单胞菌菌株中染色体β-内酰胺酶基因的温度依赖性表达
J Med Microbiol. 1987 Nov;24(3):263-5. doi: 10.1099/00222615-24-3-263.
10
In-vitro activity of ceftazidime against Pseudomonas aeruginosa: and its stability to pseudomonal beta-lactamases.头孢他啶对铜绿假单胞菌的体外活性及其对铜绿假单胞菌β-内酰胺酶的稳定性。
J Antimicrob Chemother. 1981 Sep;8 Suppl B:163-7. doi: 10.1093/jac/8.suppl_b.163.

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1
Gambling-related suicide in East African Community countries: evidence from press media reports.东非共同体国家与赌博相关的自杀：来自新闻媒体报道的证据。
BMC Public Health. 2022 Jan 24;22(1):158. doi: 10.1186/s12889-021-12306-2.
2
Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins.β-内酰胺酶AmpC突变增加铜绿假单胞菌分离株对抗假单胞菌头孢菌素的耐药性。
Antimicrob Agents Chemother. 2015 Oct;59(10):6248-55. doi: 10.1128/AAC.00825-15. Epub 2015 Jul 27.
3
Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase.铜绿假单胞菌中MexAB - OprM外排泵与β - 内酰胺酶相互作用导致对β - 内酰胺类抗生素耐药
Antimicrob Agents Chemother. 1999 May;43(5):1301-3. doi: 10.1128/AAC.43.5.1301.
4
Resistance of Pseudomonas aeruginosa to new beta-lactamase-resistant beta-lactams.铜绿假单胞菌对新型耐β-内酰胺酶β-内酰胺类药物的耐药性。
Antimicrob Agents Chemother. 1984 Oct;26(4):485-8. doi: 10.1128/AAC.26.4.485.
5
Mechanisms of resistance to cephalosporin antibiotics.对头孢菌素类抗生素的耐药机制。
Drugs. 1987;34 Suppl 2:64-88. doi: 10.2165/00003495-198700342-00007.
6
Emergence of imipenem-resistant Pseudomonas aeruginosa during treatment of intra-abdominal infection in a patient with ovarian carcinoma.一名卵巢癌患者腹腔感染治疗期间出现耐亚胺培南铜绿假单胞菌。
J Natl Med Assoc. 1988 Oct;80(10):1133-5.
7
Selection and properties of Pseudomonas aeruginosa variants resistant to beta-lactam antibiotics.
Eur J Clin Microbiol. 1987 Aug;6(4):467-73. doi: 10.1007/BF02013112.
8
Resistant strains of Pseudomonas aeruginosa isolated after exposure to several beta-lactam antibiotics.在接触多种β-内酰胺类抗生素后分离出的铜绿假单胞菌耐药菌株。
Eur J Clin Microbiol. 1987 Feb;6(1):22-7. doi: 10.1007/BF02097185.
9
Role of beta-lactamase in in vivo development of ceftazidime resistance in experimental Pseudomonas aeruginosa endocarditis.β-内酰胺酶在实验性铜绿假单胞菌心内膜炎中头孢他啶耐药性体内发展中的作用。
Antimicrob Agents Chemother. 1987 Feb;31(2):253-8. doi: 10.1128/AAC.31.2.253.
10
Evidence for multiple forms of type I chromosomal beta-lactamase in Pseudomonas aeruginosa.铜绿假单胞菌中I型染色体β-内酰胺酶多种形式的证据。
Antimicrob Agents Chemother. 1986 Sep;30(3):453-7. doi: 10.1128/AAC.30.3.453.

本文引用的文献

1
Resistance to cefamandole: derepression of beta-lactamases by cefoxitin and mutation in Enterobacter cloacae.对头孢孟多的耐药性：头孢西丁对β-内酰胺酶的去阻遏作用及阴沟肠杆菌中的突变。
J Infect Dis. 1982 Jul;146(1):34-42. doi: 10.1093/infdis/146.1.34.
2
Mutational enzymatic resistance of Enterobacter species to beta-lactam antibiotics.肠杆菌属细菌对β-内酰胺类抗生素的突变酶耐药性。
Antimicrob Agents Chemother. 1982 Apr;21(4):655-60. doi: 10.1128/AAC.21.4.655.
3
Trapping of nonhydrolyzable cephalosporins by cephalosporinases in Enterobacter cloacae and Pseudomonas aeruginosa as a possible resistance mechanism.阴沟肠杆菌和铜绿假单胞菌中的头孢菌素酶截留不可水解头孢菌素作为一种可能的耐药机制。
Antimicrob Agents Chemother. 1982 May;21(5):711-7. doi: 10.1128/AAC.21.5.711.
4
Novel resistance selected by the new expanded-spectrum cephalosporins: a concern.新型广谱头孢菌素所选择的新型耐药性：一个值得关注的问题。
J Infect Dis. 1983 Mar;147(3):585-9. doi: 10.1093/infdis/147.3.585.
5
beta-Lactam-resistant Pseudomonas aeruginosa with modified penicillin-binding proteins emerging during cystic fibrosis treatment.在囊性纤维化治疗期间出现的具有修饰青霉素结合蛋白的β-内酰胺耐药铜绿假单胞菌。
Antimicrob Agents Chemother. 1981 May;19(5):705-11. doi: 10.1128/AAC.19.5.705.
6
Characterization of beta-lactamase induction in Enterobacter cloacae.阴沟肠杆菌中β-内酰胺酶诱导的特征分析。
Antimicrob Agents Chemother. 1983 Jan;23(1):91-7. doi: 10.1128/AAC.23.1.91.
7
Chromosomal beta-lactamases of Enterobacter cloacae are responsible for resistance to third-generation cephalosporins.阴沟肠杆菌的染色体β-内酰胺酶是导致对第三代头孢菌素耐药的原因。
Antimicrob Agents Chemother. 1983 Jun;23(6):918-25. doi: 10.1128/AAC.23.6.918.
8
Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels.银染聚丙烯酰胺凝胶中沙门氏菌脂多糖化学型之间的形态异质性。
J Bacteriol. 1983 Apr;154(1):269-77. doi: 10.1128/jb.154.1.269-277.1983.
9
The use of analytical isoelectric focusing for detection and identification of beta-lactamases.利用分析性等电聚焦技术检测和鉴定β-内酰胺酶。
J Gen Microbiol. 1975 May;88(1):169-78. doi: 10.1099/00221287-88-1-169.
10
Properties of the penicillin-binding proteins of Escherichia coli K12,大肠杆菌K12青霉素结合蛋白的特性
Eur J Biochem. 1977 Jan;72(2):341-52. doi: 10.1111/j.1432-1033.1977.tb11258.x.

铜绿假单胞菌染色体β-内酰胺酶调控改变的突变体对哌拉西林、头孢他啶和头孢磺啶的耐药性。

Resistance of Pseudomonas aeruginosa mutants with altered control of chromosomal beta-lactamase to piperacillin, ceftazidime, and cefsulodin.

作者信息

Bryan L E, Kwan S, Godfrey A J

出版信息

Antimicrob Agents Chemother. 1984 Mar;25(3):382-4. doi: 10.1128/AAC.25.3.382.

DOI:10.1128/AAC.25.3.382
PMID:6426382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC185525/
Abstract

Examination of beta-lactam susceptibility of mutants altered in the control of chromosomal beta-lactamase of Pseudomonas aeruginosa supports the view that a constitutive level of beta-lactamase is not an adequate explanation for resistance to cefsulodin and ceftazidime but could be for resistance to piperacillin which has an efficiency of hydrolysis ca. 10 times higher than does cefsulodin or ceftazidime.

摘要

对铜绿假单胞菌染色体β-内酰胺酶调控发生改变的突变体进行β-内酰胺敏感性检测，支持以下观点：β-内酰胺酶的组成型水平并不能充分解释对头孢磺啶和头孢他啶的耐药性，但可能是对哌拉西林耐药的原因，哌拉西林的水解效率比头孢磺啶或头孢他啶高约10倍。