Department of Gastrointestinal Surgery and Surgical Oncology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, 791-0295, Japan.
Surg Endosc. 2017 Nov;31(11):4431-4437. doi: 10.1007/s00464-017-5493-1. Epub 2017 Apr 4.
Elderly patients usually have concurrent ailments, and the safety and effectiveness of laparoscopy-assisted distal gastrectomy (LADG) for these patients have been controversial. This study aimed to evaluate whether laparoscopy-assisted distal gastrectomy is safe and effective for elderly patients aged 80 years and over, as well as to clarify their long-term prognosis.
A total of 31 patients aged 80 years and over who underwent LADG in our hospital were retrospectively reviewed. Peri- and postoperative data were compared with those of 38 patients aged 65 years and younger. The median follow-up period of the elderly and younger group was 56.0 and 63.0 months, respectively, and their prognosis was examined.
There were significant differences between the two groups in preoperative respiratory and renal functions, hemoglobin, and nutritional index. Significant differences in postoperative complications were seen only in pneumonia and delirium. There were no hospital deaths, but the 3-year and 5-year overall survival rates were significantly lower in the elderly group than in the non-elderly group. However, in the elderly group, only one patient died of gastric cancer recurrence, whereas four died of cardiovascular disease and three died of pneumonia during follow-up. Therefore, the recurrence-free survival rate was not significantly different between the groups.
LADG seems to be safe and effective even for elderly patients, and their prognosis was satisfactory. However, careful monitoring for cardiovascular and pulmonary disease should be observed during the follow-up period.
老年患者通常伴有多种疾病,腹腔镜辅助远端胃切除术(LADG)在这些患者中的安全性和有效性存在争议。本研究旨在评估腹腔镜辅助远端胃切除术是否对 80 岁及以上的老年患者安全有效,并阐明其长期预后。
回顾性分析我院 31 例 80 岁及以上行 LADG 的患者,与 38 例 65 岁以下患者的围手术期和术后数据进行比较。老年组和年轻组的中位随访时间分别为 56.0 和 63.0 个月,对其预后进行了检查。
两组患者术前呼吸和肾功能、血红蛋白和营养指标存在显著差异。仅在肺炎和谵妄方面观察到术后并发症的显著差异。两组均无院内死亡,但老年组 3 年和 5 年总生存率明显低于非老年组。然而,在老年组中,只有 1 例患者死于胃癌复发,而在随访期间,4 例死于心血管疾病,3 例死于肺炎。因此,两组间无复发生存率无显著差异。
LADG 似乎对老年患者也是安全有效的,其预后令人满意。然而,在随访期间应密切监测心血管和肺部疾病。