子痫患者中免疫反应性前列腺素E、F及6-酮-前列腺素F1的中心静脉浓度
Central venous concentrations of immunoreactive prostaglandins E, F, and 6-keto-prostaglandin F1 in eclampsia.
作者信息
Moodley J, Norman R J, Reddi K
出版信息
Br Med J (Clin Res Ed). 1984 May 19;288(6429):1487-9. doi: 10.1136/bmj.288.6429.1487.
Abstract
Concentrations of prostaglandins E, F, and 6-keto-prostaglandin F1 alpha were estimated in central venous blood and amniotic fluid in 21 women with eclampsia and 16 healthy pregnant controls. Central venous blood concentrations of 6-keto-prostaglandin F1 alpha and prostaglandin E were significantly lower in patients than controls before delivery and remained reduced for at least 48 hours after delivery. Low concentrations of prostaglandins E and 6-keto-prostaglandin F1 alpha are probably directly related to the pathogenesis of eclampsia.
摘要
对21例子痫患者及16例健康孕妇对照者的中心静脉血和羊水进行了前列腺素E、F及6-酮-前列腺素F1α浓度的测定。子痫患者分娩前中心静脉血中6-酮-前列腺素F1α和前列腺素E的浓度显著低于对照组，且产后至少48小时仍维持在较低水平。前列腺素E和6-酮-前列腺素F1α浓度较低可能与子痫的发病机制直接相关。
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Reduced umbilical and placental vascular prostacyclin in severe pre-eclampsia.重度子痫前期患者脐血管和胎盘血管前列环素水平降低。
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