铁和钆螯合物作为核磁共振成像造影剂的初步研究。

Iron and gadolinium chelates as contrast agents in NMR imaging: preliminary studies.

作者信息

Carr D H, Brown J, Leung A W, Pennock J M

出版信息

J Comput Assist Tomogr. 1984 Jun;8(3):385-9. doi: 10.1097/00004728-198406000-00003.

DOI:10.1097/00004728-198406000-00003

Abstract

Iron (Fe2+) and gadolinium (Gd3+) chelated to ethylenediaminetetraacetic acid and Gd3+ chelated to diethylenetriamine pentaacetic acid have been used as contrast agents in nuclear magnetic resonance imaging of the normal kidney and cerebral infarction in rabbits. All three agents produced observable changes with inversion-recovery images and marked changes in T1.

摘要

与乙二胺四乙酸螯合的铁（Fe2+）和钆（Gd3+）以及与二乙烯三胺五乙酸螯合的Gd3+已被用作家兔正常肾脏和脑梗死的核磁共振成像造影剂。这三种造影剂在反转恢复图像上均产生了可观察到的变化，且在T1上有明显变化。