Hirsig J, Baals H, Tuchschmid P, Spitz L, Stauffer U G
J Pediatr Surg. 1984 Apr;19(2):155-7. doi: 10.1016/s0022-3468(84)80436-4.
Two cases of infantile dumping syndrome which developed following Nissen fundoplication for gastroesophageal reflux are described. Both infants were fed postoperatively via a gastrostomy and showed the typical clinical picture of dumping with failure to thrive, intermittent diarrhea, lethargy and pallor postprandially. Several glucose tolerance tests were highly pathological with marked hyperglycemia immediately after a gastrostomy meal followed by hypoglycemia two hours later. In one case HbA1c was significantly elevated which is thought to be an expression of recurrent hyperglycemia. In both infants the first and most impressive clinical sign was absolute refusal or oral feeds. Normal oral food intake was slowly re-established after normalization of blood glucose homeostasis.
本文描述了两例因胃食管反流行nissen胃底折叠术后发生婴儿倾倒综合征的病例。两名婴儿术后均通过胃造口喂养，呈现出典型的倾倒临床症状，包括生长发育迟缓、间歇性腹泻、餐后嗜睡和面色苍白。多次葡萄糖耐量试验结果显示高度异常，胃造口餐后立即出现明显高血糖，两小时后出现低血糖。其中一例糖化血红蛋白（HbA1c）显著升高，这被认为是反复高血糖的一种表现。两名婴儿最初且最明显的临床症状都是完全拒绝经口喂养。血糖内环境稳定恢复正常后，正常经口食物摄入得以缓慢恢复。
