Villet R, Boureau M, Hayat P, Weisgerber G
Chir Pediatr. 1978 Jul-Aug;19(4):269-73.
A rare complication of Nissen's operation is described on the basis of four cases. Appearing secondarily, its Clinical signs are hyperperistaltic diarrhea, without bacterial infection and a fall or levelling of the weight curve. Its constant features are:--acceleration of intestinal transit and principally of gastric evacuation;--a characteristic modification of glucose absorption and of the curve of the oral glucose tolerance test compared with the normal intravenous glucose tolerance test. Overload of dissacharides in the intestine and hypervagotony could explain the symptomatology, which responds with difficulty and sometimes only partially to a diet excluding rapidly absorbed surgars. This complication supervenes often in babies operated on at less than six months, and is an indication for post ponement of operation.
基于4例病例描述了尼森手术的一种罕见并发症。该并发症继发出现，临床症状为蠕动亢进性腹泻，无细菌感染，体重曲线下降或趋于平稳。其恒定特征为：——肠道转运加速，主要是胃排空加速；——与正常静脉葡萄糖耐量试验相比，葡萄糖吸收及口服葡萄糖耐量试验曲线有特征性改变。肠道双糖过载和迷走神经功能亢进可解释这些症状，对排除快速吸收糖类的饮食，该并发症反应困难，有时仅部分有效。这种并发症常发生于6个月以下接受手术的婴儿，是推迟手术的指征。
