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用于评估血浆纤维蛋白原浓度的血凝块重量法与放射免疫扩散法的相关性。

Correlation of a clot-weight and radial immunodiffusion method for estimation of plasma fibrinogen concentration.

作者信息

Reid H L, Onwuameze I C

出版信息

Trop Geogr Med. 1984 Mar;36(1):13-6.

PMID:6428012
Abstract

A clot-weight and radial immunodiffusion method for estimating fibrinogen concentration were compared using plasma from 58 pregnant women and diabetic patients. The two methods gave a correlation coefficient, r = 0.53 (p less than 0.005). There was no significant variation between the mean fibrinogen concentrations as determined by both methods. The coefficient of variation for the clot-weight and immunodiffusion methods were 1.54% and 2.9%, respectively. It is concluded that the clot-weight method is more readily applicable than the radial immunodiffusion method to fibrinogen measurements, especially in patients when rapid results are required.

摘要

使用58名孕妇和糖尿病患者的血浆,对用于估算纤维蛋白原浓度的凝块重量法和放射免疫扩散法进行了比较。两种方法的相关系数r = 0.53(p < 0.005)。两种方法测定的平均纤维蛋白原浓度之间无显著差异。凝块重量法和免疫扩散法的变异系数分别为1.54%和2.9%。得出的结论是,凝块重量法比放射免疫扩散法更易于应用于纤维蛋白原测量,尤其是在需要快速结果的患者中。

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