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伴有盆腔淋巴结受累的前列腺癌的放射治疗

Radiotherapeutic treatment of prostatic carcinoma with pelvic node involvement.

作者信息

Bagshaw M A

出版信息

Urol Clin North Am. 1984 May;11(2):297-304.

PMID:6428023
Abstract

Resolution of pelvic lymph node metastases following irradiation can be demonstrated clinically by relief of obstructive symptoms and objectively by shrinkage of adenopathy as demonstrated by lymphography. Nevertheless, survival following nodal irradiation for patients with surgically proved pelvic or periaortic adenopathy or both at 10 years is only 20 per cent, whereas without adenopathy it is nearly 80 per cent. In spite of this relatively low level of survival, the firm documentation of survival without evidence of lymph node disease in 9 of 60 patients is ample justification for irradiation of regional lymphatics in these high-risk patients.

摘要

盆腔淋巴结转移灶经照射后的消退可通过梗阻症状的缓解在临床上得到证实,并且可通过淋巴管造影显示的腺病缩小在客观上得到证实。然而,经手术证实有盆腔或主动脉旁腺病或两者皆有的患者,接受淋巴结照射后的10年生存率仅为20%,而无腺病患者的生存率接近80%。尽管生存率相对较低,但60例患者中有9例在无淋巴结疾病证据的情况下生存的明确记录,足以证明对这些高危患者的区域淋巴管进行照射是合理的。

相似文献

1
Radiotherapeutic treatment of prostatic carcinoma with pelvic node involvement.伴有盆腔淋巴结受累的前列腺癌的放射治疗
Urol Clin North Am. 1984 May;11(2):297-304.
2
Long-term follow-up of patients with prostate cancer and nodal metastases treated by pelvic lymphadenectomy and radical prostatectomy: the positive impact of adjuvant radiotherapy.接受盆腔淋巴结清扫术和根治性前列腺切除术治疗的前列腺癌伴淋巴结转移患者的长期随访:辅助放疗的积极影响
Eur Urol. 2009 May;55(5):1003-11. doi: 10.1016/j.eururo.2009.01.046. Epub 2009 Feb 4.
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Radical cystectomy and extended pelvic lymphadenectomy: survival of patients with lymph node metastasis above the bifurcation of the common iliac vessels treated with surgery only.根治性膀胱切除术和扩大盆腔淋巴结清扫术:仅接受手术治疗的髂总血管分叉以上淋巴结转移患者的生存率。
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Pelvic nodal dose escalation with prostate hypofractionation using conformal avoidance defined (H-CAD) intensity modulated radiation therapy.使用适形避让定义的(H-CAD)调强放射治疗对前列腺低分割放疗时盆腔淋巴结剂量递增。
Acta Oncol. 2006;45(6):717-27. doi: 10.1080/02841860600781781.
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[Risk factors and prognosis of node-positive cervical carcinoma].[淋巴结阳性宫颈癌的危险因素及预后]
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Radiotherapy of prostatic carcinoma: long- or short-term efficacy (Stanford University experience).前列腺癌的放射治疗:长期或短期疗效(斯坦福大学经验)
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Radiation Therapy Oncology Group studies in carcinoma of the prostate.放射治疗肿瘤学组关于前列腺癌的研究。
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Lack of benefit of pelvic radiation in prostate cancer patients with a high risk of positive pelvic lymph nodes treated with high-dose radiation.对于盆腔淋巴结转移风险高且接受高剂量放疗的前列腺癌患者,盆腔放疗并无益处。
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Pelvic lymph node irradiation for prostate cancer: who, why, and when?前列腺癌的盆腔淋巴结照射:哪些人、为何以及何时进行?
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Is there a role for pelvic irradiation in localized prostate adenocarcinoma? Preliminary results of GETUG-01.盆腔放疗在局限性前列腺腺癌中是否有作用?GETUG-01的初步结果。
J Clin Oncol. 2007 Dec 1;25(34):5366-73. doi: 10.1200/JCO.2006.10.5171.

引用本文的文献

1
Intensity-modulated radiotherapy (IMRT) to prostate and pelvic nodes-is pelvic lymph node coverage adequate with fiducial-based image-guided radiotherapy?前列腺及盆腔淋巴结调强放射治疗(IMRT)——基于基准点的图像引导放射治疗对盆腔淋巴结的覆盖是否足够?
Br J Radiol. 2014 May;87(1037):20130696. doi: 10.1259/bjr.20130696. Epub 2014 Mar 20.
2
[Locally advanced prostate carcinoma (T2b-T4 N0) without and with clinical evidence of local progression (Tx N+) with lymphatic metastasis. Is radiotherapy for pelvic lymphatic metastasis indicated or not?].[局部进展期前列腺癌(T2b - T4 N0),有无局部进展的临床证据(Tx N+)伴淋巴转移。盆腔淋巴转移是否需要进行放射治疗?]
Strahlenther Onkol. 1998 May;174(5):231-6. doi: 10.1007/BF03038714.
3
Iodine 125 interstitial irradiation for localized prostate cancer.
碘125间质照射治疗局限性前列腺癌。
J Natl Med Assoc. 1990 Mar;82(3):181-93.
4
Is deleting the digital rectal examination a good idea?取消直肠指检是个好主意吗?
West J Med. 1991 Jul;155(1):43-6.
5
Histological and immunohistochemical findings of prostatic carcinoma after external or interstitial radiotherapy.外照射或组织间放疗后前列腺癌的组织学和免疫组化结果
J Cancer Res Clin Oncol. 1991;117(6):608-14. doi: 10.1007/BF01613297.