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桔橙粘球菌素,一种来自橙色粘球菌(粘杆菌目)的新型抗生素。I. 生产、理化性质及生物学特性

Stigmatellin, a new antibiotic from Stigmatella aurantiaca (Myxobacterales). I. Production, physico-chemical and biological properties.

作者信息

Kunze B, Kemmer T, Höfle G, Reichenbach H

出版信息

J Antibiot (Tokyo). 1984 May;37(5):454-61. doi: 10.7164/antibiotics.37.454.

Abstract

An antibiotic activity was extracted from the cell mass of the myxobacterium, Stigmatella aurantiaca strain Sg a15. The antibiotic was toxic for yeasts and filamentous fungi, but not for most bacteria. The compound had the molecular formula C30H42O7, appears to be a new antibiotic, and was named stigmatellin. In addition to stigmatellin, the strain produced relatively large quantities of a second, structurally unrelated antibiotic, a mixture of three myxalamid homologues.

摘要

从橙色粘球菌菌株Sg a15的细胞团中提取出了一种抗生素活性物质。该抗生素对酵母和丝状真菌有毒,但对大多数细菌无毒。该化合物的分子式为C30H42O7,似乎是一种新抗生素,被命名为粘球菌素。除了粘球菌素外,该菌株还产生了相对大量的第二种结构不相关的抗生素,即三种粘菌素同系物的混合物。

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