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黏液螯菌素A,一种来自盘状血管球菌(黏细菌目)的新型铁螯合化合物。生产、分离、理化性质及生物学特性。

Myxochelin A, a new iron-chelating compound from Angiococcus disciformis (Myxobacterales). Production, isolation, physico-chemical and biological properties.

作者信息

Kunze B, Bedorf N, Kohl W, Höfle G, Reichenbach H

机构信息

GBF, Gesellschaft für Biotechnologische Forschung mbH, Arbeitsgruppe Sekundärstoffe aus Mikroorganismen, Braunschweig, FRG.

出版信息

J Antibiot (Tokyo). 1989 Jan;42(1):14-7. doi: 10.7164/antibiotics.42.14.

Abstract

Myxochelin A, a new catechole siderophore, was isolated from the culture broth of the myxobacterium, Angiococcus disciformis strain An d30. As is the case with other iron-chelating compounds the production of myxochelin A could be markedly increased up to 44 mg/liter by fermentation at low iron concentrations (10(-7) M FeCl3). The new substance showed weak activity against some bacteria.

摘要

黏液菌素A是一种新的儿茶酚型铁载体,从黏细菌盘状血管球菌菌株An d30的培养液中分离得到。与其他铁螯合化合物一样,在低铁浓度(10⁻⁷ M FeCl₃)下发酵时,黏液菌素A的产量可显著提高至44毫克/升。这种新物质对某些细菌表现出微弱的活性。

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