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接受盆腔放射治疗的年轻女性卵巢功能的保留

The preservation of ovarian function in young women undergoing pelvic radiation therapy.

作者信息

Husseinzadeh N, Nahhas W A, Velkley D E, Whitney C W, Mortel R

出版信息

Gynecol Oncol. 1984 Jul;18(3):373-9. doi: 10.1016/0090-8258(84)90049-0.

DOI:10.1016/0090-8258(84)90049-0
PMID:6430756
Abstract

Because cervical carcinoma rarely metastasizes to the ovaries, it became logical to preserve ovarian function by the method of lateral ovarian transposition as part of the management of young women with this disease. This technique prevents castration should subsequent radiation therapy be planned or become necessary. Forty patients with carcinoma of the cervix or vagina underwent unilateral or bilateral ovarian transposition. Eighteen patients received radiation therapy. Of these, 16 had gonadotropin measurements and only 6 (37%) had levels elevated to the postmenopausal range. If patients whose ovaries were not shielded or who received paraaortic radiotherapy are excluded, then only two (17%) had elevated gonadotropin values. It is concluded that, if properly performed, lateral ovarian transposition and ovarian shielding will protect ovarian function in patients receiving pelvic radiotherapy.

摘要

由于宫颈癌很少转移至卵巢,因此对于患有该疾病的年轻女性,作为治疗的一部分,通过卵巢侧方移位术来保留卵巢功能成为合理的做法。如果随后计划进行放射治疗或有必要进行放射治疗,该技术可防止卵巢切除。40例宫颈癌或阴道癌患者接受了单侧或双侧卵巢移位术。18例患者接受了放射治疗。其中16例进行了促性腺激素检测,只有6例(37%)的促性腺激素水平升高至绝经后范围。如果排除卵巢未受屏蔽或接受腹主动脉旁放疗的患者,那么只有2例(17%)促性腺激素值升高。得出的结论是,如果操作得当,卵巢侧方移位术和卵巢屏蔽将保护接受盆腔放疗患者的卵巢功能。

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The preservation of ovarian function in young women undergoing pelvic radiation therapy.接受盆腔放射治疗的年轻女性卵巢功能的保留
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