Sato M, Ishidoya T, Joko Y, Kiyasu Y, Sakai K, Kimura S
Gan No Rinsho. 1984 Jun;30(7):805-9.
Constant intra-aortic infusion chemotherapy using an artificial graft was performed in 39 patients with advanced abdominal cancer. This method was easy for insertion and re-insertion of the catheter; thus it is suitable for long-term and repeated constant infusion therapy. Complications encountered with the catheter were obstruction (8 cases); cracking (4 cases); cracking of the connector (4 cases); infection of the graft (2 cases), and arterial thrombosis (1 case). Minor complications encountered upon using the catheter were solved by our method, however, infection represents a serious problem. In cases with peritoneal metastases, the response rate was excellent (43% by Karnofsky's criterion and 67% as determined by the ascitic effect) and this therapy was effective for symptoms resulting from peritoneal metastases. In conclusion, ours seems to be useful therapeutic method for advanced abdominal cancer with peritoneal metastases.
对39例晚期腹部癌症患者采用人工血管进行持续主动脉内灌注化疗。该方法便于导管的插入和重新插入；因此适用于长期和重复的持续灌注治疗。导管出现的并发症有阻塞（8例）；破裂（4例）；接头破裂（4例）；人工血管感染（2例）和动脉血栓形成（1例）。使用导管时遇到的轻微并发症通过我们的方法得以解决，然而，感染是一个严重问题。在有腹膜转移的病例中，缓解率极佳（根据卡诺夫斯基标准为43%，根据腹水效果确定为67%），且该疗法对腹膜转移引起的症状有效。总之，我们的方法似乎是治疗伴有腹膜转移的晚期腹部癌症的有效治疗方法。
