van Bijsterveld O P
Acta Ophthalmol (Copenh). 1984 Jun;62(3):479-84. doi: 10.1111/j.1755-3768.1984.tb08428.x.
In a placebo controlled double-blind crossover study, 60 patients with chronic non-infections conjunctivitis were treated for 4 weeks with either sodium cromoglycate eye drops or with placebo followed by 4 weeks on the alternative treatment. The dose was one drop into each eye 4 times daily. The scores for a number of symptoms and signs were significantly lower after 4 weeks sodium cromoglycate treatment than after similar placebo treatment. In both the patients' and clinician's opinion significantly more patients responded to the active treatment than to the placebo treatment. At the end of the trial clinician recorded more preferences for sodium cromoglycate (27) than for placebo (9), and the difference was highly significant (P less than 0.01). No side effects were reported during the trial.
在一项安慰剂对照的双盲交叉研究中，60例慢性非感染性结膜炎患者接受了4周的色甘酸钠滴眼液治疗或安慰剂治疗，随后交叉接受4周的另一种治疗。剂量为每日4次，每眼滴入一滴。经过4周的色甘酸钠治疗后，多项症状和体征的评分显著低于类似的安慰剂治疗后。在患者和临床医生看来，对活性治疗有反应的患者明显多于对安慰剂治疗有反应的患者。在试验结束时，临床医生记录的对色甘酸钠（27例）的偏好多于对安慰剂（9例），差异具有高度显著性（P小于0.01）。试验期间未报告副作用。
