[胃蛋白酶晶体热膨胀系数的测定。酶球构象动力学的各向异性]
[Determination of the heat expansion coefficient of pepsin crystals. Anisotropy of conformation dynamics of the enzyme globule].
作者信息
Frank E G, Namiot V A, Esipova N G
出版信息
Biofizika. 1984 May-Jun;29(3):494-6.
PMID:6432063
Abstract
The microscopic study of heat expansion of monoclinic pepsin crystals was performed in temperature interval of -120 degrees C to +20 degrees C. The coefficient of heat expansion along the C axis was shown to be 8-10 times as large as along the B axis. This dynamics anisotropy is interpreted to reflect the domain mobility of the molecule.
摘要
在-120℃至+20℃的温度区间内对单斜晶型胃蛋白酶晶体的热膨胀进行了微观研究。结果表明，沿C轴的热膨胀系数比沿B轴的热膨胀系数大8至10倍。这种动力学各向异性被解释为反映了分子的结构域迁移率。
相似文献
1
2
HEAT- AND ALKALI-INDUCED CHANGES IN THE CONFORMATION OF PEPSINOGEN AND PEPSIN.热和碱诱导的胃蛋白酶原及胃蛋白酶构象变化
Biochemistry. 1963 Sep-Oct;2:964-71. doi: 10.1021/bi00905a012.
3
PARTIAL CHARACTERIZATION OF HUMAN PEPSIN I, PEPSIN IIA, PEPSIN IIB, AND PEPSIN 3.人胃蛋白酶I、胃蛋白酶IIA、胃蛋白酶IIB和胃蛋白酶3的部分特性分析
Biochemistry. 1964 Sep;3:1203-9. doi: 10.1021/bi00897a003.
4
[Two stages in the digestion of proteins by pepsin].[胃蛋白酶消化蛋白质的两个阶段]
Nahrung. 1976;20(6):593-6.
5
[X-ray analysis of pepsin. VI. Atomic structure of the enzyme at 2-angstrom resolution].胃蛋白酶的X射线分析。VI. 2埃分辨率下该酶的原子结构
Mol Biol (Mosk). 1984 Mar-Apr;18(2):313-22.
6
7
[Physical state of crystalline proteins. IV. Melting of trypsin and pepsin crystals].[结晶蛋白质的物理状态。IV. 胰蛋白酶和胃蛋白酶晶体的熔化]
Biofizika. 1976 Jul-Aug;21(4):750-2.
8
Microcalorimetry of thermal denaturation of pepsin and trypsin in the crystal state.胃蛋白酶和胰蛋白酶晶体状态热变性的微量量热法
Biochim Biophys Acta. 1976 May 20;434(1):286-9. doi: 10.1016/0005-2795(76)90060-x.
9
[Dependence of pepsin conformational states on pH and temperature].[胃蛋白酶构象状态对pH值和温度的依赖性]
Biokhimiia. 1979 Feb;44(2):339-49.
10
[Physico-chemical characterization and crystallization of immunoglobulins and their fragments: a contribution to the three dimensional structural determination of antibodies. V. The F(ab')2-fragment of human immunoglobulin Kol; isolation and crystallization].免疫球蛋白及其片段的物理化学特性与结晶：对抗体三维结构测定的贡献。V. 人免疫球蛋白Kol的F(ab')2片段；分离与结晶
Biol Chem Hoppe Seyler. 1989 Mar;370(3):259-61.
Zotero 插件