McMurchie E J, Gibson R A, Charnock J S, McIntosh G H
Comp Biochem Physiol B. 1984;78(4):817-26. doi: 10.1016/0305-0491(84)90193-7.
Rats and marmosets were fed different lipid supplemented diets and the phospholipid fatty acid composition and the respiration rate of liver and heart mitochondria were determined. For both species, diets of differing lipid saturation had little effect on the ratio of saturated to unsaturated fatty acids in the mitochondrial membranes, however the omega 6/omega 3 unsaturated fatty acid ratio was significantly altered by diets of different lipid saturation. In comparison to animals fed low fat diets, mitochondrial respiration in the marmoset was reduced by high fat diets irrespective of the dietary level of lipid saturation. This effect of high fat diets on mitochondrial respiration was not observed for the rat.
给大鼠和狨猴喂食不同的添加脂质饮食,并测定肝脏和心脏线粒体的磷脂脂肪酸组成以及呼吸速率。对于这两个物种,不同脂质饱和度的饮食对线粒体膜中饱和脂肪酸与不饱和脂肪酸的比例影响不大,然而,不同脂质饱和度的饮食会显著改变ω-6/ω-3不饱和脂肪酸的比例。与喂食低脂饮食的动物相比,无论脂质饱和度的饮食水平如何,高脂肪饮食都会降低狨猴的线粒体呼吸。在大鼠中未观察到高脂肪饮食对线粒体呼吸的这种影响。