麻风病患者血清中补体C3成分的转化
Conversion of the C3 component of complement in sera of hanseniasis patients.
作者信息
Kliemann T A, Martinez E L, Irulegui I, de Souza Z W, Cavalcanti Z M
出版信息
Hansenol Int. 1983 Jun;8(1):5-8.
The levels of total C3 (native C3 plus its degradation products) and the degree of conversion of native C3 into its breakdown products were studied in sera of Virchowian (V), tuberculoid (T), indeterminate (I), and Virchowian with erythema nodosum Hansenicum (ENH) patients. Sera from normal individuals (N) were also analysed. While the levels of total C3 were not significantly different among the groups, the percentage of conversion of C3 into its degradation products was significantly higher in V and ENH sera. The activation of the complement system and the involvement of immune complexes (IC) are discussed.
在结节病（V）、结核样型（T）、未定类（I）以及结节性红斑型汉森病（ENH）患者的血清中，研究了总C3水平（天然C3及其降解产物）以及天然C3向其分解产物的转化程度。还分析了正常个体（N）的血清。虽然各组之间总C3水平无显著差异，但V组和ENH组血清中C3转化为其降解产物的百分比显著更高。讨论了补体系统的激活以及免疫复合物（IC）的参与情况。
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