γ干扰素抑制伯氏考克斯体在小鼠成纤维细胞中的生长。
Interferon-gamma inhibits growth of Coxiella burnetii in mouse fibroblasts.
作者信息
Turco J, Thompson H A, Winkler H H
出版信息
Infect Immun. 1984 Sep;45(3):781-3. doi: 10.1128/iai.45.3.781-783.1984.
Abstract
We studied the effects of various mouse interferon preparations on the growth of Coxiella burnetii in mouse fibroblasts. The addition of both recombinant interferon-gamma and a crude lymphokine preparation that contained interferon-gamma to infected L929 cells inhibited the growth of C. burnetii, whereas the addition of a crude preparation of type I interferons did not. Cycloheximide suppressed the inhibitory effects of recombinant interferon-gamma and crude lymphokines.
摘要
我们研究了多种小鼠干扰素制剂对伯氏考克斯氏体在小鼠成纤维细胞中生长的影响。向感染的L929细胞中添加重组干扰素-γ和含有干扰素-γ的粗制淋巴因子制剂均能抑制伯氏考克斯氏体的生长，而添加I型干扰素的粗制制剂则不能。放线菌酮可抑制重组干扰素-γ和粗制淋巴因子的抑制作用。
相似文献
1
Interferon-gamma inhibits growth of Coxiella burnetii in mouse fibroblasts.γ干扰素抑制伯氏考克斯体在小鼠成纤维细胞中的生长。
Infect Immun. 1984 Sep;45(3):781-3. doi: 10.1128/iai.45.3.781-783.1984.
2
Cloned mouse interferon-gamma inhibits the growth of Rickettsia prowazekii in cultured mouse fibroblasts.克隆的小鼠干扰素-γ可抑制普氏立克次体在培养的小鼠成纤维细胞中的生长。
J Exp Med. 1983 Dec 1;158(6):2159-64. doi: 10.1084/jem.158.6.2159.
3
Viable Coxiella burnetii Induces Differential Cytokine Responses in Chronic Q Fever Patients Compared to Heat-Killed Coxiella burnetii.活的贝氏考克斯体与热灭活的贝氏考克斯体相比，可诱导慢性 Q 热患者产生不同的细胞因子反应。
Infect Immun. 2018 Sep 21;86(10). doi: 10.1128/IAI.00333-18. Print 2018 Oct.
4
Intact interferon-γ response against Coxiella burnetii by peripheral blood mononuclear cells in chronic Q fever.慢性 Q 热患者外周血单个核细胞对柯克斯体的完整干扰素-γ反应。
Clin Microbiol Infect. 2017 Mar;23(3):209.e9-209.e15. doi: 10.1016/j.cmi.2016.11.008. Epub 2016 Nov 20.
5
Immune response and Coxiella burnetii invasion.免疫应答与柯克斯体感染。
Adv Exp Med Biol. 2012;984:287-98. doi: 10.1007/978-94-007-4315-1_15.
6
Specific interferon γ detection for the diagnosis of previous Q fever.针对既往 Q 热的诊断进行特定干扰素 γ 的检测。
Clin Infect Dis. 2013 Jun;56(12):1742-51. doi: 10.1093/cid/cit129. Epub 2013 Mar 5.
7
Comparison of the properties of antirickettsial activity and interferon in mouse lymphokines.小鼠淋巴因子中抗立克次氏体活性与干扰素特性的比较。
Infect Immun. 1983 Oct;42(1):27-32. doi: 10.1128/iai.42.1.27-32.1983.
8
IFN-gamma-mediated control of Coxiella burnetii survival in monocytes: the role of cell apoptosis and TNF.干扰素-γ介导的单核细胞中伯氏考克斯氏体存活的调控：细胞凋亡和肿瘤坏死因子的作用
J Immunol. 1999 Feb 15;162(4):2259-65.
9
A combination of interferon-gamma and interleukin-2 production by Coxiella burnetii-stimulated circulating cells discriminates between chronic Q fever and past Q fever.贝氏柯克斯体刺激循环细胞产生的干扰素-γ和白细胞介素-2的组合可区分慢性 Q 热和既往 Q 热。
Clin Microbiol Infect. 2014 Jul;20(7):642-50. doi: 10.1111/1469-0691.12423. Epub 2013 Nov 18.
10
Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro.小鼠肺泡巨噬细胞在体外对贝氏柯克斯体Ⅱ相的复制高度敏感。
Infect Immun. 2016 Aug 19;84(9):2439-48. doi: 10.1128/IAI.00411-16. Print 2016 Sep.
引用本文的文献
1
QuilA® adjuvanted Coxevac® sustains Th1-CD8-type immunity and increases protection in Coxiella burnetii-challenged goats.QuilA®佐剂的Coxevac®维持Th1-CD8型免疫，并增强对感染伯氏考克斯氏体山羊的保护作用。
NPJ Vaccines. 2023 Feb 14;8(1):17. doi: 10.1038/s41541-023-00607-z.
2
TGF-β/IFN-γ Antagonism in Subversion and Self-Defense of Phase II Coxiella burnetiiInfected Dendritic Cells.TGF-β/IFN-γ 拮抗作用在二期伯氏考克斯体感染树突状细胞中的颠覆和自卫。
Infect Immun. 2023 Feb 16;91(2):e0032322. doi: 10.1128/iai.00323-22. Epub 2023 Jan 23.
3
Coxiella burnetii-Infected NK Cells Release Infectious Bacteria by Degranulation.贝纳柯克斯体感染的自然杀伤细胞通过脱颗粒释放感染性细菌。
Infect Immun. 2020 Oct 19;88(11). doi: 10.1128/IAI.00172-20.
4
Eosinophils Affect Antibody Isotype Switching and May Partially Contribute to Early Vaccine-Induced Immunity against Coxiella burnetii.嗜酸性粒细胞影响抗体同种型转换，并可能部分有助于早期疫苗诱导对柯克斯体的免疫。
Infect Immun. 2019 Oct 18;87(11). doi: 10.1128/IAI.00376-19. Print 2019 Nov.
5
Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In Vitro.小鼠肺泡巨噬细胞在体外对贝氏柯克斯体Ⅱ相的复制高度敏感。
Infect Immun. 2016 Aug 19;84(9):2439-48. doi: 10.1128/IAI.00411-16. Print 2016 Sep.
6
Exploratory study on Th1 epitope-induced protective immunity against Coxiella burnetii infection.Th1表位诱导的针对伯氏考克斯氏体感染的保护性免疫的探索性研究。
PLoS One. 2014 Jan 30;9(1):e87206. doi: 10.1371/journal.pone.0087206. eCollection 2014.
7
Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii.柯克斯体（Coxiella burnetii）这种严格的细胞内细菌的分子发病机制。
Nat Rev Microbiol. 2013 Aug;11(8):561-73. doi: 10.1038/nrmicro3049. Epub 2013 Jun 24.
8
Adaptive immunity to the obligate intracellular pathogen Coxiella burnetii.对专性胞内病原体伯纳特立克次体的适应性免疫。
Immunol Res. 2009;43(1-3):138-48. doi: 10.1007/s12026-008-8059-4.
9
Attenuated Coxiella burnetii phase II causes a febrile response in gamma interferon knockout and Toll-like receptor 2 knockout mice and protects against reinfection.减毒的贝氏柯克斯体II期菌株在γ干扰素基因敲除小鼠和Toll样受体2基因敲除小鼠中引起发热反应，并能预防再次感染。
Infect Immun. 2007 Dec;75(12):5845-58. doi: 10.1128/IAI.00901-07. Epub 2007 Sep 24.
10
Coxiella burnetii inhibits apoptosis in human THP-1 cells and monkey primary alveolar macrophages.伯纳特立克次氏体抑制人THP-1细胞和猴原代肺泡巨噬细胞的凋亡。
Infect Immun. 2007 Sep;75(9):4263-71. doi: 10.1128/IAI.00594-07. Epub 2007 Jul 2.
本文引用的文献
1
STAINING RICKETTSIAE IN YOLK-SAC CULTURES.卵黄囊培养物中里克次氏体的染色
Stain Technol. 1964 May;39:135-40. doi: 10.3109/10520296409061219.
2
The biology of rickettsiae.立克次氏体生物学
Annu Rev Microbiol. 1982;36:345-70. doi: 10.1146/annurev.mi.36.100182.002021.
3
Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan.γ干扰素通过诱导宿主细胞降解色氨酸来阻断弓形虫在人成纤维细胞中的生长。
Proc Natl Acad Sci U S A. 1984 Feb;81(3):908-12. doi: 10.1073/pnas.81.3.908.
4
Cloned mouse interferon-gamma inhibits the growth of Rickettsia prowazekii in cultured mouse fibroblasts.克隆的小鼠干扰素-γ可抑制普氏立克次体在培养的小鼠成纤维细胞中的生长。
J Exp Med. 1983 Dec 1;158(6):2159-64. doi: 10.1084/jem.158.6.2159.
5
Lymphokine-mediated inhibition of Chlamydia replication in mouse fibroblasts is neutralized by anti-gamma interferon immunoglobulin.抗γ干扰素免疫球蛋白可中和淋巴细胞因子介导的对小鼠成纤维细胞中衣原体复制的抑制作用。
Infect Immun. 1983 Dec;42(3):1152-8. doi: 10.1128/iai.42.3.1152-1158.1983.
6
Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine.淋巴因子刺激的人单核吞噬细胞对细胞内杜氏利什曼原虫的杀伤作用。γ干扰素是激活淋巴因子的证据。
J Clin Invest. 1983 Oct;72(4):1506-10. doi: 10.1172/JCI111107.
7
Comparison of the properties of antirickettsial activity and interferon in mouse lymphokines.小鼠淋巴因子中抗立克次氏体活性与干扰素特性的比较。
Infect Immun. 1983 Oct;42(1):27-32. doi: 10.1128/iai.42.1.27-32.1983.
8
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.鉴定γ干扰素为激活人类巨噬细胞氧化代谢和抗菌活性的淋巴因子。
J Exp Med. 1983 Sep 1;158(3):670-89. doi: 10.1084/jem.158.3.670.
9
Inhibition of the growth of Rickettsia prowazekii in cultured fibroblasts by lymphokines.淋巴因子对培养的成纤维细胞中普氏立克次体生长的抑制作用。
J Exp Med. 1983 Mar 1;157(3):974-86. doi: 10.1084/jem.157.3.974.
10
Q fever and Coxiella burnetii: a model for host-parasite interactions.Q热与贝纳柯克斯体：宿主-寄生虫相互作用的一个模型
Microbiol Rev. 1983 Jun;47(2):127-49. doi: 10.1128/mr.47.2.127-149.1983.
Zotero 插件