Samaranayake L P, Calman K C, Ferguson M M, Kaye S B, MacFarlane T W, Main B, Welsh J, Willox J
J Oral Pathol. 1984 Aug;13(4):390-3. doi: 10.1111/j.1600-0714.1984.tb01438.x.
The oral carriage of yeasts and coliforms in a healthy adult population and a group of patients with malignancies, undergoing cytotoxic therapy was investigated. A quantitative increase in the intra-oral carriage of Candida species and coliforms was observed during cytotoxic therapy. The most frequent yeast and the coliform isolated were Candida albicans and Escherichia coli, respectively. Thus, the oral cavity may constitute a reservoir of potentially pathogenic flora in patients on cytotoxic therapy.
对健康成年人群以及一组正在接受细胞毒性治疗的恶性肿瘤患者口腔中酵母菌和大肠菌群的携带情况进行了调查。在细胞毒性治疗期间，观察到念珠菌属和大肠菌群的口腔内携带量出现定量增加。最常见的酵母菌和分离出的大肠菌群分别是白色念珠菌和大肠杆菌。因此，口腔可能构成接受细胞毒性治疗患者潜在致病菌群的储存库。
