Ichimaru H, Nakamura M
Yale J Biol Med. 1983 Sep-Dec;56(5-6):761-3.
A plaque-forming agent arose spontaneously during cloning of Acholeplasma oculi 19L. The agent produced plaques on A. oculi 19L and A. oculi-i, but not on A. laidlawii, A. modicum, or wild isolates of A. oculi. The agent required horse serum for plaque formation as well as for adsorption to the indicator lawn; however, it was extremely sensitive to an inhibitor in some horse sera. The agent retained infectivity after passage through a 50 nm filter and was heat-, Nonidet P-40-, and chloroform-labile, but relatively ether-stable. It was not determined whether the agent is a virus or a bacteriocin-like substance.
在眼支原体19L株的克隆过程中，一种噬菌斑形成因子自发出现。该因子能在眼支原体19L株和眼支原体-i上形成噬菌斑，但不能在莱氏无胆甾原体、眼支原体适量株或眼支原体野生分离株上形成。该因子形成噬菌斑以及吸附到指示菌苔都需要马血清；然而，它对某些马血清中的一种抑制剂极为敏感。该因子通过50纳米滤膜传代后仍保持感染性，对热、非离子去污剂NP-40和氯仿不稳定，但对乙醚相对稳定。尚未确定该因子是一种病毒还是一种类细菌素物质。
