Watanabe M, Watanabe Z, Sasaki T, Yamao N, Tanji H, Kodama N, Sato Y, Honda T, Endo S
No Shinkei Geka. 1984 Jul;12(8):995-9.
An autopsy case of intracranial multiple meningiomas associated with extracranial multiple neurinomas was presented. A 55-year-old woman, who had received surgical treatment for right parasagittal meningioma 20 years ago, gradually showed the sign of increased intracranial pressure and disturbance of the lower cranial nerves. Brain CT scan demonstrated numerous intracranial tumors. At autopsy 124 intracranial meningiomas, and neurinomas in her left cervical and right axillar portion were found. Meningiomas showed the transitional and fibroblastic type, histopathologically, and axillary and cervical tumors were the Antoni A type neurinomas. It is suggested that this case had a tendency of heterogenous and multiple origination of tumors.
本文报告一例颅内多发性脑膜瘤合并颅外多发性神经鞘瘤的尸检病例。一名55岁女性,20年前因右矢状窦旁脑膜瘤接受手术治疗,逐渐出现颅内压增高和下颅神经功能障碍的症状。脑部CT扫描显示颅内有大量肿瘤。尸检发现颅内有124个脑膜瘤,左颈部和右腋窝部有神经鞘瘤。组织病理学检查显示脑膜瘤为过渡型和成纤维细胞型,腋窝和颈部肿瘤为Antoni A型神经鞘瘤。提示该病例具有肿瘤异质性和多源性的倾向。