Singh B S
Psychosom Med. 1984 Jul-Aug;46(4):347-62. doi: 10.1097/00006842-198407000-00004.
The prominence of respiratory symptoms in patients with neurotic psychiatric disorders is noted and the literature on the control of respiration is reviewed to attempt to explain this finding. A previous study demonstrated a positive correlation between the ventilatory response to CO2 (S) and neurotic personality traits in a group of normal subjects. This study attempted to follow up this finding and hypothesized that a group of neurotically disturbed patients would have a higher S value and a group of individuals who practiced a calming technique such as transcendental meditation (TM) would have a lower S value than normal subjects. The second hypothesis was confirmed, but not the first, in that the neurotically disturbed patients had the lowest mean values for S of the three groups, rather than the highest. Particular characteristics of the sample of psychiatric patients cast doubt, however, on the validity of this finding. Three additional findings of this study were that anxious, depressive, and hyperventilating subject groups were no different from one another in terms of S values; that very experienced TM practitioners (sidhas) could significantly lower their ventilatory response to CO2 in the meditating state as compared to the nonmeditating alert state; and that the S value did not increase in two male subjects with endogenous depression after successful treatment with electroconvulsive therapy.
已注意到神经症性精神障碍患者中呼吸症状的突出性，并回顾了关于呼吸控制的文献，试图解释这一发现。先前的一项研究表明，一组正常受试者中对二氧化碳的通气反应（S）与神经症人格特质之间存在正相关。本研究试图跟进这一发现，并假设一组患有神经症性障碍的患者将具有较高的S值，而一组练习诸如超觉静坐（TM）等平静技巧的个体的S值将低于正常受试者。第二个假设得到了证实，但第一个假设未得到证实，因为患有神经症性障碍的患者在三组中S的平均值最低，而不是最高。然而，精神病患者样本的特殊特征对这一发现的有效性提出了质疑。本研究的另外三个发现是，焦虑、抑郁和换气过度的受试者组在S值方面彼此没有差异；与非冥想警觉状态相比，经验丰富的TM练习者（悉达）在冥想状态下可显著降低其对二氧化碳的通气反应；并且两名患有内源性抑郁症的男性受试者在接受电休克治疗成功后，S值并未增加。
