Post R M, Weiss S R, Pert A
Prog Neuropsychopharmacol Biol Psychiatry. 1984;8(3):425-34.
Lithium carbonate appears to inhibit the development of cocaine-induced behavioral sensitization while it does not inhibit the development of amygdala kindling. Lithium chloride did not inhibit kindled seizures. Carbamazepine does not inhibit cocaine-induced motor activity or the development of behavioral sensitization in the rat. Carbamazepine is highly effective in blocking completed amygdala-kindled seizures, but does not block their development in the rat. Lithium carbonate and carbamazepine, two drugs of use in the prophylactic treatment of affective illness, appear to have differential effects on sensitization and kindling.
碳酸锂似乎能抑制可卡因诱导的行为敏化的发展，而不抑制杏仁核点燃的发展。氯化锂不抑制点燃性癫痫发作。卡马西平不抑制可卡因诱导的大鼠运动活动或行为敏化的发展。卡马西平在阻断已完成的杏仁核点燃性癫痫发作方面非常有效，但不阻断其在大鼠中的发展。碳酸锂和卡马西平这两种用于情感性疾病预防性治疗的药物，似乎对敏化和点燃有不同的作用。
