Galeeva O P, Ruzal' G I, Lukashkov V M, Gazizova G R
Zh Mikrobiol Epidemiol Immunobiol. 1984 Aug(8):44-7.
The study of the action of 12 Neisseria species belonging to 112 strains, 6 B. catarrhalis strains and 202 meningococcal strains on the culture of continuous cell line F1 (human amniotic cells) has revealed that nonpathogenic Neisseria are essentially weaker than meningococci in their pathogenicity (expressed in terms of CPD50). Among nonpathogenic Neisseria highly cytopathogenic strains occur in 13.9% of cases, which gives grounds for considering them opportunistic bacteria. Sharply pronounced correlation between the adhesive and pathogenic properties of Neisseria has been observed. The cytopathogenic action of Neisseria is accompanied by the lesion of the chromosomal apparatus of mitotic infected cells.
对属于112株的12种奈瑟菌、6株卡他莫拉菌和202株脑膜炎球菌对连续细胞系F1（人羊膜细胞）培养物的作用研究表明，非致病性奈瑟菌在致病性方面（以CPD50表示）本质上比脑膜炎球菌弱。在非致病性奈瑟菌中，13.9%的病例出现高细胞致病性菌株，这使人们有理由将它们视为机会致病菌。已观察到奈瑟菌的黏附特性与致病特性之间存在明显的相关性。奈瑟菌的细胞致病作用伴随着有丝分裂感染细胞染色体装置的损伤。
