Sjöström A, Conradi N G, Andersson S A
Acta Physiol Scand. 1984 Apr;120(4):585-94. doi: 10.1111/j.1748-1716.1984.tb07424.x.
During an investigation focused on development of visual evoked responses (VER) in normal and protein deprived rats indications of persisting latency differences were found. Since such differences are in variance with previous reports special attention was paid to compare control and protein deprived adult rats. Protein deprivation was induced by feeding rats a diet with 50% reduction in protein content compared with control rat diet from two weeks before onset of gestation until examination. Dependence on experimental variables of latencies and complexity of the VER illustrated the need of a well defined experimental situation. Adult protein deprived rats showed significantly longer latencies to onset and to the first three peaks of the VER and an altered complexity of the response. It is suggested that the observed alterations result from effects of the protein deprivation on early brain development since this and previous studies have shown similar alterations in developing young rats. The divergence in findings between the present and previous reports may be explained by differences in degree of malnutrition and in other experimental conditions.
在一项针对正常和蛋白质缺乏大鼠视觉诱发电位（VER）发育的研究中，发现了持续存在的潜伏期差异迹象。由于这种差异与先前的报告不一致，因此特别关注比较对照成年大鼠和蛋白质缺乏成年大鼠。从妊娠开始前两周到检查时，通过给大鼠喂食蛋白质含量比对照大鼠饮食减少50%的饮食来诱导蛋白质缺乏。VER潜伏期和复杂性对实验变量的依赖性表明需要一个定义明确的实验环境。成年蛋白质缺乏大鼠的VER起始潜伏期和前三个波峰潜伏期明显更长，且反应复杂性改变。有人认为，观察到的变化是蛋白质缺乏对早期大脑发育的影响所致，因为本研究和先前的研究表明，发育中的幼鼠也有类似变化。本报告与先前报告结果的差异可能是由于营养不良程度和其他实验条件的不同所致。
