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[克氏锥虫的同工酶菌株:起源是近期还是古老,是同源还是异源?]

[Isoenzymatic strains of Trypanosoma cruzi: recent or ancient, homogeneous or heterogeneous origin?].

作者信息

Tibayrenc M, Solignac M, Cariou M L, Le Ray D, Desjeux P

出版信息

C R Acad Sci III. 1984;299(7):195-8.

PMID:6435816
Abstract

Genetic variability studied among 13 Trypanosoma cruzi laboratory reference stocks confirms the existence of three principal isozymic categories. As the main part of enzymic variability is now recognized, it seems possible to attribute any stock to the taxon T. cruzi with safety. Genetic parameters allow to infer two main hypotheses relative to the evolutionary origin of these categories: ancient origin (either by mitotic evolution or by speciation), or recent origin (by clone sampling among a sexual ancestral population). The possibility of a heterogeneous origin of the strains is discussed.

摘要

对13株克氏锥虫实验室参考菌株的遗传变异性研究证实了三种主要同工酶类别的存在。由于现在已认识到酶变异性的主要部分,因此似乎可以安全地将任何菌株归为克氏锥虫分类单元。遗传参数有助于推断出与这些类别的进化起源相关的两个主要假设:古老起源(通过有丝分裂进化或物种形成),或近期起源(通过有性祖先群体中的克隆抽样)。本文还讨论了菌株起源异质性的可能性。

相似文献

1
[Isoenzymatic strains of Trypanosoma cruzi: recent or ancient, homogeneous or heterogeneous origin?].[克氏锥虫的同工酶菌株:起源是近期还是古老,是同源还是异源?]
C R Acad Sci III. 1984;299(7):195-8.
2
[Taxonomic and medical status of isoenzyme strains of Trypanosoma cruzi. Considerations of the systematic and immunologic values of various isoenzymes].[克氏锥虫同工酶株的分类学和医学地位。对各种同工酶的系统发育和免疫学价值的思考]
C R Seances Acad Sci III. 1983;296(15):721-6.
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Genetic variation among Trypanosoma cruzi populations.克氏锥虫种群间的遗传变异。
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Clonal population structure of Colombian sylvatic Trypanosoma cruzi.哥伦比亚野生克氏锥虫的克隆群体结构
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Trypanosoma cruzi: isoenzyme analysis suggests the presence of an active Chagas sylvatic cycle of recent origin in Paraná State, Brazil.克氏锥虫:同工酶分析表明,巴西巴拉那州存在一个近期起源的活跃的查加斯病野生动物循环。
Exp Parasitol. 2002 Feb;100(2):81-6. doi: 10.1016/S0014-4894(02)00009-7.
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Genetic variability of Colombian populations of Trypanosoma cruzi and Trypanosoma rangeli.克氏锥虫和兰氏锥虫哥伦比亚种群的遗传变异性。
Biol Res. 1999;32(1):1-10.
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[High correlation between isoenzyme classification and kinetoplast DNA variability in Trypanosoma cruzi].[克氏锥虫同工酶分类与动基体DNA变异性之间的高度相关性]
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Trypanosoma cruzi: variability of stocks from Colombia determined by molecular karyotype and minicircle Southern blot analysis.克氏锥虫:通过分子核型和小环Southern印迹分析确定的来自哥伦比亚的虫株变异性
Exp Parasitol. 2006 May;113(1):62-6. doi: 10.1016/j.exppara.2005.11.016. Epub 2006 Jan 4.
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Diversity of Trypanosoma cruzi stocks and clones derived from Chagas disease patients. II. Isozyme and RFLP characterizations.源自恰加斯病患者的克氏锥虫株系和克隆的多样性。II. 同工酶和限制性片段长度多态性特征分析
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Enzyme variation among clones of Trypanosoma cruzi.克氏锥虫克隆之间的酶变异
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引用本文的文献

1
Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure.恰加斯病的病原体克氏锥虫的自然种群具有复杂的多克隆结构。
Proc Natl Acad Sci U S A. 1986 Jan;83(1):115-9. doi: 10.1073/pnas.83.1.115.