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犬类血友病,特别提及丹麦德国牧羊犬中的甲型血友病。I:病理生理学、实验室检查及遗传学

Hemophilia in dogs, with special reference to hemophilia A among German shepherd dogs in Denmark. I: Pathophysiology, laboratory tests and genetics.

作者信息

Fogh J M, Nygaard L, Andresen E, Nilsson I M

出版信息

Nord Vet Med. 1984 Jul-Aug;36(7-8):235-40.

PMID:6436787
Abstract

A review is given of the history and distribution of hemophilia in dogs. The current knowledge of Factor VIII relative to hemophilia A and von Willebrand's Disease is presented. The tests required for distinguishing between hemophilia A, hemophilia B, von Willebrand's Disease, and various disorders caused by other factor defects in the coagulation cascade are described. X-linked, recessive inheritance of hemophilia A is illustrated in genealogical diagrams. The precautions required in connection with blood sampling for diagnostic tests are emphasized.

摘要

本文综述了犬血友病的历史及分布情况。介绍了与甲型血友病和血管性血友病相关的凝血因子VIII的现有知识。描述了区分甲型血友病、乙型血友病、血管性血友病以及凝血级联反应中其他因子缺陷引起的各种疾病所需的检测方法。系谱图展示了甲型血友病的X连锁隐性遗传。强调了诊断性检测采血时所需的预防措施。

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Hemophilia in dogs, with special reference to hemophilia A among German shepherd dogs in Denmark. I: Pathophysiology, laboratory tests and genetics.犬类血友病,特别提及丹麦德国牧羊犬中的甲型血友病。I:病理生理学、实验室检查及遗传学
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