Curzen P, Bekir J S, McLintock D G, Patel M
Br Med J (Clin Res Ed). 1984 Nov 17;289(6455):1345-7. doi: 10.1136/bmj.289.6455.1345.
A prospective study of 6825 labours was undertaken to determine the relation between the Apgar scores of the babies at one minute and the cardiotocograph tracing in labour. The sensitivity of an abnormal tracing was 35.2% for babies who needed intermittent positive pressure ventilation and 20.0% for babies who did not but who had Apgar scores of less than 7. The sensitivity of an abnormal tracing for all babies with an Apgar score of less than 7 was 23.2%. The positive predictive value of an abnormal tracing was 8.7% for babies who needed intermittent positive pressure ventilation and 18.7% for babies who did not but who had an Apgar score of less than 7. The positive predictive value of an abnormal tracing was 27.4% for all babies with an Apgar score of less than 7. The specificity of the tracing was 93.4% for babies with an Apgar score of 7 or over. The relatively high incidence of false positive predictions might be explained on the grounds that abnormalities in the cardiotocograph tracing are a more sensitive indicator of hypoxia than the Apgar score. False negative predictions might have been due to adverse factors other than hypoxia--for example, fetal trauma, compression of the head, infection, and analgesia in labour. These findings suggest that the current overdependence on fetal monitoring by cardiotocography alone should be examined and that other reliable indicators for non-hypoxic fetal distress should be sought.
对6825例分娩进行了一项前瞻性研究,以确定婴儿出生一分钟时的阿氏评分与分娩时胎心监护图之间的关系。对于需要间歇性正压通气的婴儿,异常监护图的敏感性为35.2%;对于不需要但阿氏评分低于7分的婴儿,异常监护图的敏感性为20.0%。对于所有阿氏评分低于7分的婴儿,异常监护图的敏感性为23.2%。对于需要间歇性正压通气的婴儿,异常监护图的阳性预测值为8.7%;对于不需要但阿氏评分低于7分的婴儿,异常监护图的阳性预测值为18.7%。对于所有阿氏评分低于7分的婴儿,异常监护图的阳性预测值为27.4%。对于阿氏评分7分及以上的婴儿,监护图的特异性为93.4%。假阳性预测的相对高发生率可能是因为胎心监护图异常比分娩时的阿氏评分更能敏感地提示缺氧。假阴性预测可能是由于缺氧以外的其他不利因素,如胎儿创伤、头部受压、感染和分娩时的镇痛。这些发现表明,应审视目前对单纯胎心监护的过度依赖,并应寻找其他非缺氧性胎儿窘迫的可靠指标。