米斯塔布隆对血小板和血液凝固的影响。
Mistabron effects on platelets and blood coagulation.
作者信息
Henry R L, Washnock M A, Taylor G W
出版信息
J Int Med Res. 1984;12(5):277-80. doi: 10.1177/030006058401200502.
PMID:6437891
Abstract
The mucolytic drug Mistabron is often used in bleeding situations. The purpose of this study is to assess the safety of this drug in such circumstances. The platelet function of human blood is not impaired by clinically used Mistabron dosage, after stimulation with epinephrine, ADP or arachidonic acid. Coagulation proteins are not modified by Mesna, neither in vitro (blood from human beings), nor in vivo (rats).
摘要
黏液溶解药物氨溴索常被用于出血情况。本研究的目的是评估该药物在此类情况下的安全性。经肾上腺素、二磷酸腺苷或花生四烯酸刺激后，临床使用剂量的氨溴索不会损害人体血液的血小板功能。美司钠在体外（人体血液）和体内（大鼠）均不会改变凝血蛋白。
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