Wang X, Liao F L, Stoltz J F
Equipe Hémorhéologie-Angiohématologie, Laboratoire d'Energétique et de Mécanique Théorique et Appliquée, UMR CNRS 7563, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.
Clin Hemorheol Microcirc. 1998 Sep;19(1):25-31.
The aim of this work was to evaluate a new automatic cone-plate viscometer (LBY-N6, PRECIL, Beijing, China) which was designed for clinical measurements of blood and plasma viscosities. Standard calibrating oils of viscosity varying from 1.85 to 20.5 mPas (conforming to ASTM Standard) were used to test the precision and reproducibility of the device. Then the viscometer was used to measure blood and plasma viscosities. The results were compared with those obtained with a conventional Couette viscometer and a capillary viscometer. The results showed that this new viscometer gave good values of viscosity for standard oils with relative errors lower than 10% at shear rates ranging from 20 to 200 s(-1). It also had a good reproducibility (standard deviations < 3% in most cases). Only the results at low shear rates (< 10 s(-1)) were less identical. As for blood, the relative difference between the results given by LBY-N6 and those obtained by Low Shear 30 was less than 10% at high shear rates. This difference decreased with shear rate and could be partly caused by viscoelastic and thixotropic properties of human blood. A small difference between the values of plasma viscosity obtained by LBY-N6 and the capillary viscometer AMTEC was also observed. In conclusion, this new viscometer can be used a routine tool to determine quickly plasma and blood viscosities in clinical practice at shear rates higher than 20 s(-1).
这项工作的目的是评估一种新型自动锥板粘度计（LBY-N6，普力生，中国北京），该粘度计专为临床测量血液和血浆粘度而设计。使用粘度范围为1.85至20.5 mPas的标准校准油（符合ASTM标准）来测试该设备的精度和重现性。然后使用该粘度计测量血液和血浆粘度。将结果与使用传统库埃特粘度计和毛细管粘度计获得的结果进行比较。结果表明，对于标准油，这种新型粘度计在20至200 s(-1)的剪切速率下给出了良好的粘度值，相对误差低于10%。它还具有良好的重现性（在大多数情况下标准偏差<3%）。只有低剪切速率（<10 s(-1)）下的结果不太一致。对于血液，在高剪切速率下，LBY-N6给出的结果与Low Shear 30获得的结果之间的相对差异小于10%。这种差异随剪切速率降低，可能部分是由人体血液的粘弹性和触变性引起的。还观察到LBY-N6获得的血浆粘度值与毛细管粘度计AMTEC之间存在微小差异。总之，这种新型粘度计可作为一种常规工具，在临床实践中以高于20 s(-1)的剪切速率快速测定血浆和血液粘度。
