Schörner W, Felix R, Claussen C, Fiegler W, Kazner E, Speck U, Niendorf H P
Rofo. 1984 Nov;141(5):511-6. doi: 10.1055/s-2008-1053181.
This study examines the effect of the NMR contrast medium gadolinium-DTPA on image contrast in cerebral tumours. Sixteen patients with space-occupying cerebral lesions were examined on a 0.35 Tesla superconducting scanner, using a T1-weighted spinecho sequence prior to and after the intravenous application of gadolinium-DTPA. In 8 patients T2-weighted spinecho-sequences were obtained before the administration of contrast. The tomograms were evaluated visually and according to quantitative criteria. The use of gadolinium-DTPA helps to evaluate the blood-brain barrier and improves diagnosis by differentiating tumour tissue from edema and from normal brain tissue.
本研究探讨了核磁共振造影剂钆-DTPA对脑肿瘤图像对比度的影响。对16例患有脑部占位性病变的患者，在0.35特斯拉超导扫描仪上，于静脉注射钆-DTPA之前和之后，使用T1加权自旋回波序列进行检查。8例患者在注射造影剂之前还获得了T2加权自旋回波序列。通过视觉和定量标准对断层扫描图像进行评估。钆-DTPA的使用有助于评估血脑屏障，并通过区分肿瘤组织与水肿以及正常脑组织来改善诊断。
