Passmore C M, McElnay J C, D'Arcy P F
Br Med J (Clin Res Ed). 1984 Dec 8;289(6458):1593-6. doi: 10.1136/bmj.289.6458.1593.
In an inpatient survey the medication records of 2004 mothers both breast and bottle feeding were examined and the drugs taken in the early postnatal period recorded. No notable differences existed between the types of drugs prescribed for breast feeding and bottle feeding mothers. Iron, vitamins, and mild analgesics were taken routinely by the population, and antibiotics, laxatives, and hypnotics were frequently prescribed. A wide range of other drugs and preparations were taken or used. Although data were available for some of the drugs, there were many whose concentrations in breast milk and potential risk to the suckling infant were unknown. Data are urgently required on hypnotics, narcotic analgesics, antiemetics, antihistaminics, and some antimicrobial agents with respect to their concentrations in breast milk and their safety for the suckling infant.
在一项住院患者调查中，对2004名母乳喂养和人工喂养母亲的用药记录进行了检查，并记录了产后早期服用的药物。母乳喂养母亲和人工喂养母亲所开药物的种类没有显著差异。该人群常规服用铁剂、维生素和轻度镇痛药，抗生素、泻药和催眠药也经常被开出处方。还服用或使用了多种其他药物和制剂。虽然有些药物有相关数据，但仍有许多药物在母乳中的浓度以及对哺乳婴儿的潜在风险尚不清楚。迫切需要关于催眠药、麻醉性镇痛药、止吐药、抗组胺药以及一些抗菌药物在母乳中的浓度及其对哺乳婴儿安全性的数据。
