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初乳乳清中的免疫球蛋白G1 Fc

Immunoglobulin G1 Fc in colostral whey.

作者信息

Nielsen K, Stiller J, Sowa B

出版信息

Can J Comp Med. 1984 Oct;48(4):410-3.

Abstract

Two IgG1 fragments were isolated from bovine colostral whey. Based on gel diffusion analysis, both fragments originated from the Fc portion of the molecule but were not identical to IgG1 Fc prepared by papain cleavage. The molecular weights were determined to be 66,000 and 14,000 daltons and it was hypothesized that the larger fragment could be a polymer of the smaller. No IgG1 Fab or IgG2 fragments could be demonstrated.

摘要

从牛初乳清中分离出两个IgG1片段。基于凝胶扩散分析,这两个片段均源自该分子的Fc部分,但与通过木瓜蛋白酶裂解制备的IgG1 Fc不同。确定其分子量分别为66,000和14,000道尔顿,并推测较大的片段可能是较小片段的聚合物。未检测到IgG1 Fab或IgG2片段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa8/1236094/ab25edbe09fc/compmed00008-0072-a.jpg

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