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流产布鲁氏菌的一种细胞外物质对乳清中牛免疫球蛋白G1的裂解作用。

Cleavage of bovine immunoglobulin G1 in whey by an extracellular material from Brucella abortus.

作者信息

Nielsen K

出版信息

Can J Comp Med. 1985 Jul;49(3):337-9.

PMID:3930059
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1236183/
Abstract

Culture extracts of in vitro grown Brucella abortus were demonstrated to cleave a part of the Fc portion of bovine immunoglobulin G1 in whey but not in serum or as a purified protein from serum. Supernates from Strains 19 and 2308 of B. abortus were both capable of this hydrolysis whereas living cells were not. The cleavage process was independent of antibody activity to B. abortus, appeared to require factor(s) found only in some whey samples and was ineffective with the other bovine immunoglobulins.

摘要

体外培养的流产布鲁氏菌的培养物提取物被证明能够切割乳清中牛免疫球蛋白G1的Fc部分，但不能切割血清中的Fc部分，也不能切割从血清中纯化的蛋白质。流产布鲁氏菌19株和2308株的上清液都有这种水解能力，而活细胞则没有。切割过程与针对流产布鲁氏菌的抗体活性无关，似乎需要仅在某些乳清样品中发现的因子，并且对其他牛免疫球蛋白无效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a8/1236183/fc1c060ca32c/compmed00003-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a8/1236183/fc1c060ca32c/compmed00003-0102-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97a8/1236183/fc1c060ca32c/compmed00003-0102-a.jpg

相似文献

1
Cleavage of bovine immunoglobulin G1 in whey by an extracellular material from Brucella abortus.流产布鲁氏菌的一种细胞外物质对乳清中牛免疫球蛋白G1的裂解作用。
Can J Comp Med. 1985 Jul;49(3):337-9.
2
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本文引用的文献

1
[A micro-method of immuno-electrophoresis].[免疫电泳的微量方法]
Int Arch Allergy Appl Immunol. 1955;7(2):103-10.
2
Hemoparasitism, humoral immunodeficiency, and an IgG1 fragment in a cow.一头奶牛的血内寄生、体液免疫缺陷及一种IgG1片段
J Am Vet Med Assoc. 1982 Sep 1;181(5):480-3.
3
Immunoglobulin G1 Fc in colostral whey.初乳乳清中的免疫球蛋白G1 Fc
Can J Comp Med. 1984 Oct;48(4):410-3.
4
Affinity purification of bovine antibodies to Brucella abortus Lipopolysaccharide.牛抗布鲁氏菌流产亚种脂多糖抗体的亲和纯化。
J Clin Microbiol. 1983 Feb;17(2):323-6. doi: 10.1128/jcm.17.2.323-326.1983.
5
Bovine immunoglobulins: an augmented review.牛免疫球蛋白：综述补充
Vet Immunol Immunopathol. 1983 Mar;4(1-2):43-152. doi: 10.1016/0165-2427(83)90056-9.
6
Evaluation of antibovine IgG subclass specific antisera from guinea pigs and goats.豚鼠和山羊抗牛IgG亚类特异性抗血清的评估。
Res Vet Sci. 1981 Sep;31(2):147-50.
7
The occurrence of immunoglobulin fragments, two types of lactoferrin and a lactoferrin-IgG2 complex in bovine colostral and milk whey.牛初乳和乳清中免疫球蛋白片段、两种乳铁蛋白及乳铁蛋白-IgG2复合物的存在情况。
Biochim Biophys Acta. 1973 Jan 25;295(1):341-51. doi: 10.1016/0005-2795(73)90101-3.
8
Production of an Fc fragment from human immunoglobulin A by an IgA-specific bacterial protease.利用IgA特异性细菌蛋白酶从人免疫球蛋白A产生Fc片段。
Adv Exp Med Biol. 1974;45(0):245-9. doi: 10.1007/978-1-4613-4550-3_29.
9
Differential susceptibility of human IgA immunoglobulins to streptococcal IgA protease.人IgA免疫球蛋白对链球菌IgA蛋白酶的敏感性差异
J Clin Invest. 1974 Dec;54(6):1295-300. doi: 10.1172/JCI107875.
10
Distribution of Brucella antibody among immunoglobulin classes and a low molecular weight antibody fraction in serum and whey of cattle.牛血清和乳清中布鲁氏菌抗体在免疫球蛋白类别及低分子量抗体组分中的分布
Res Vet Sci. 1973 May;14(3):381-4.